Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 7

  1. Cat.No. Product Name Information/Activity
  2. BCC6562 Phaclofen 114012-12-3 Phaclofen chemical structure
  3. BCC6580 Saclofen 125464-42-8 Saclofen chemical structure
  4. BCC5692 SCH 50911 SCH 50911, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM. SCH 50911 chemical structure
  5. BCC7644 rac BHFF 123557-91-5 rac BHFF chemical structure
  6. BCC7097 CGP 13501 Positive modulator at GABA<sub>B</sub> receptors CGP 13501 chemical structure
  7. BCC7096 CGP 7930 57717-80-3 CGP 7930 chemical structure
  8. BCC7233 GS 39783 39069-52-8 GS 39783 chemical structure
  9. BCC7186 N-ArachidonylGABA 128201-89-8 N-ArachidonylGABA chemical structure
  10. BCC3783 Gabapentin Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. Gabapentin chemical structure
  11. BCC6629 3-Methyl-GABA 71424-95-8 3-Methyl-GABA chemical structure

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