Asthma Research

Asthma is a common chronic inflammatory disease of the respiratory system that affects approximately 22 million people in US. It has been classified as a complex genetic condition that is determined by the interaction of numerous genes along with environmental factors.

Asthma Research Products Targets

Products for Asthma Research - Page 4

Cat.No. Product Name Information/Activity
BCC7446 UCL 2077 UCL 2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker (IC50 = 500 nM in hippocampal neurons in culture), having minimal effects on Ca2+ channels, action potentials, input resistance and the medium after hyperpolarization. UCL 2077 is also a subtype-selective blocker of the epilepsy associated KCNQ channels.
BCC5812 AF 12198 Potent, selective human type I IL-1 receptor antagonist
BCC7149 YM 90709 YM-90709 is a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.
BCC5895 Lyn peptide inhibitor 222018-18-0
BCC5813 Ro 26-4550 trifluoroacetate 1217448-66-2
BCC6223 ACHP 406208-42-2
BCC1423 BMS-345541 BMS-345541 hydrochloride is a selective inhibitor of the catalytic subunits of IKK (IKK-2 IC50=0.3 μM, IKK-1 IC50=4 μM). BMS-345541 binds at an allosteric site of IKK.
BCC6130 PF 184 1187460-81-6
BCC7949 PS 1145 dihydrochloride 1049743-58-9
BCC4554 SC-514 SC-514 is a selective IKK-2 inhibitor (IC50=11.2 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.