Atherosclerosis and Hyperlipidemia Research

Atherosclerosis is a disorder of the arteries characterized by the formation of hard structures called atherosclerotic plaques. It is a prevalent disorder, accounting for one third of all deaths in North America.

Atherosclerosis and Hyperlipidemia Research Products Targets

Products for Atherosclerosis and Hyperlipidemia Research - Page 10

Cat.No. Product Name Information/Activity
BCN5599 Baicalein Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 mM.
BCC7013 BW-B 70C 5-Lipoxygenase inhibitor
BCC7504 PD 146176 PD146176 (NSC168807) is a 15-Lipoxygenase (15-LO) inhibitor, which inhibits rabbit reticulocyte 15-LO with a Ki of 197 nM. PD146176 (NSC168807) has a dramatic effect in reducing atherogenesis.
BCC7288 STEARDA 105955-10-0
BCC6735 2-TEDC 132465-10-2
BCC2515 Zileuton Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.
BCC7412 Fexaramine Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity relative to natural compounds.
BCC3790 GW3965 HCl GW3965 hydrochloride is a potent and selective liver X receptor (LXR) agonist with EC50s of 190 and 30 nM for hLXRα and hLXRβ , respectively.
BCC4500 GW4064 GW 4064 is a potent FXR agonist with an EC50 of 65 nM.
BCN2750 27-Hydroxycholesterol 27-Hydroxycholesterol is a selective estrogen receptor modulator and an agonist of the liver X receptor.