Atherosclerosis and Hyperlipidemia Research
Atherosclerosis is a disorder of the arteries characterized by the formation of hard structures called atherosclerotic plaques. It is a prevalent disorder, accounting for one third of all deaths in North America.
Atherosclerosis and Hyperlipidemia Research Products Targets
- PI 3-kinase (22)
- HMG-CoA Reductase (8)
- Matrix Metalloprotease (16)
- LXR-like Receptor (6)
- Elastase (1)
- Cell Adhesion Molecule (21)
- Lipoxygenase (8)
- Leukotriene and Related Receptor (13)
- Others (7)
- Cyclooxygenase (24)
- Angiotensin-Converting Enzyme (8)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- NO donors and precursors (9)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- Urotensin-II Receptor (8)
- Angiotensin AT2 Receptor (3)
- Angiotensin AT1 Receptor (9)
- Phospholipase (16)
- Prostanoid Receptor (24)
- Cytokine (15)
- Platelet-Activating Factor (PAF) Receptor (5)
Products for Atherosclerosis and Hyperlipidemia Research - Page 6
- Cat.No. Product Name Information/Activity
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BCC7391
Talniflumate
66898-62-2
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BCC7419
Tenidap
Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 µM and 1.2 µM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties. Tenidap is also a specific SLC26A3 inhibitor.
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BCC4441
Valdecoxib
Valdecoxib is a highly potent and selective inhibitor of COX-2, with IC50s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain.
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BCC7886
BTZO 1
BTZO-1 binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro.
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BCC6816
Chicago Sky Blue 6B
2610-05-1
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BCC6161
(±)-CPSI 1306
(±)-CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF).
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BCC5914
ER 27319 maleate
1204480-26-1
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BCC2096
Gabexate mesylate
Gabexate mesylate is a Factor X inhibitor; serine protease inhibitor .
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BCC5203
VGX-1027
VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.
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BCC5773
10Z-Hymenialdisine
82005-12-7


