Others - BioCrick

Cat.No. Product Name Information/Activity

BCC6056 SB 328437 247580-43-4 SB 328437 chemical structure

BCC6057 Teijin compound 1 CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM. Teijin compound 1 chemical structure

BCC4447 Plerixafor 8HCl (AMD3100 8HCl) Plerixafor octahydrochloride (AMD3100 octahydrochloride) is a selective CXCR4 antagonist with an IC50 of 44 nM.

Plerixafor 8HCl (AMD3100 8HCl) chemical structure

BCC5182 AMD 3465 hexahydrobromide AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC50s of 0.75 nM and 18 nM in SupT1 cells; AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM), but has no effect on CCR5-using (R5) viruses. AMD 3465 hexahydrobromide chemical structure

AMD 3465 hexahydrobromide chemical structure

BCC6366 CTCE 9908 1030384-98-5 CTCE 9908 chemical structure

BCC7917 FC 131 606968-52-9 FC 131 chemical structure

BCC6234 IT1t dihydrochloride IT1t dihydrochloride is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. IT1t dihydrochloride chemical structure

BCC8077 SB 225002 SB225002, a potent, selective and non-peptide CXCR2 antagonist, inhibits 125I-IL-8 binding to CXCR2 with an IC50 of 22 nM. SB 225002 chemical structure

BCC5936 SB 265610 SB-265610 is a selective, competitive, nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s of 3.7 nM and 70 nM, respectively. SB 265610 chemical structure

BCC7910 TC 14012 368874-34-4 TC 14012 chemical structure

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