Products for CFTR
- Cat.No. Product Name Information
-
BCC1664
Ivacaftor hydrate
Ivacaftor hydrate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.
-
BCC1663
Ivacaftor benzenesulfonate
Ivacaftor benzenesulfonate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.
-
BCC1241
VX-661
Tezacaftor (VX-661) is a second F508del CFTR corrector and help CFTR protein reach the cell surface.
-
BCC3922
IOWH-032
IOWH-032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays.
-
BCC4419
CFTRinh-172
CFTR(inh)-172 is a potent and selective blocker of the CFTR chloride channel; reversibly inhibits CFTR short-circuit current in less than 2 minutes with a Ki of 300 nM.
-
BCC4104
GlyH-101
GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.
-
BCC3881
PTC124 (Ataluren)
Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor.
-
BCC2478
Ivacaftor (VX-770)
Ivacaftor is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.
-
BCC5248
PPQ-102
PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride current with IC50 of ~90 nM.
-
BCC3712
VX-809
Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein.
