Products with
Anti-platelet aggregation bioactivity
Cat.No.
|
Product Name
|
BCN3555 |
Procurcumenol
|
1. Procurcumenol is inhibitors of Nitric Oxide.
2. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a). |
BCN3559 |
Curcolone
|
1. Curcolone exhibits inhibition against collagen-induced platelet aggregation at 100 uM, it also inhibit arachidonic acid (AA)-induced platelet aggregation at 100 uM. |
BCN3571 |
Broussoflavonol F
|
1. Broussoflavonol F has antiplatelet effect, is partially due to an inhibitory effect on cyclooxygenase, can inhibit arachidonic acid (AA)-induced platelet aggregation.
2. Broussoflavonol F shows inhibitory activities on mushroom tyrosinase.
3. Broussoflavonol F shows radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), the IC50 value of 708.54 uM.
4. Broussoflavonol F exhibits moderate cytotoxic activities against five human cancer cells with the IC50 value of 0.41-7.2 ug/mL. |
BCN3627 |
Kadsulignan L
|
1. Kadsulignan L shows in vitro antiviral effects on hepatitis B virus.
2. Kadsulignan L shows moderate platelet-activating factor (PAF) antagonistic activities with the IC50 value of 2.6 x 10(-5) M. |
BCN3671 |
Loureirin A
|
Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs. |