Products with Anti-platelet aggregation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4037 | Piplartine |
| 1. Piplartine shows potential anti-malaria and anti- leishmaniasis activities. 2. Piplartine shows inhibitory activities of platelet aggregation induced by ADP and AA in vitro . 3. Piplartine displays in vitro and in vivo anticancer efficacy. 4. Piplartine induces in vivo and in vitro mutagenicity in eukaryotic models. | |
| BCN4043 | Pellitorine |
| 1. Pellitorine shows strong cytotoxic activities against HL60 and MCT-7 cell lines. 2. Pellitorine can suppress expression of inducible NO synthase and cyclooxygenase-2. 3. Pellitorine shows antiprotozoal activity against Plasmodium falciparum (IC50 = 3.3 ug/mL). 4. Pellitorine is a potential larvicide with a specific target site and a lead molecule for the control of mosquito populations. 5. Pellitorine shows potent antiplatelet aggregation activity. | |
| BCN4081 | Cycloolivil |
| 1. (+)-Cycloolivil and oleuropein are natural polyphenolic compounds with a significant radical scavenging activity present in olive tree, they can reduce the ability of thrombin to stimulate platelet aggregation, this effect is greater in platelets from patients with type 2 diabetes mellitus than in controls;suggest that they may prevent thrombotic complications associated to platelet hyperaggregability and be the base for the development of antiaggregant therapeutic strategies. 2. (+)-Cycloolivil is an antioxidant. | |
| BCN4082 | 3'-Methoxydaidzein |
| 1. 3'-Methoxydaidzein and geraldol have antiplatelet aggregation activity and appear to be specific against collagen‐induce platelet aggregation with a IC50 values of12.3 and 61.5 uM, respectively. 2. 3'-Methoxydaidzein has antioxidant activity. | |
| BCN4086 | 1-Cinnamoylpyrrolidine |
| 1-Cinnamoylpyrrolidine shows inhibitory activity of platelet aggregation in vitro. | |
