Products with Anti-platelet aggregation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5380 | Scutellarein |
| Scutellarein has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities, it can improve neuronal injury, has better protective effect in rat cerebral ischemia. Scutellarein may serve as a SARS-CoV chemical inhibitor, it also exerts strong inhibition towards the tested UDP-glucuronosyltransferase isoforms. | |
| BCN5455 | Pinusolidic acid |
| 1. Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 +/- 2.11 micrograms/ml). | |
| BCN5477 | Acuminatin |
| 1. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity against platelet aggregation with IC50 values of 108.5 and 90.02 uM, respectively. 2. (-)-Acuminatin, and machilin G show dose-dependent potent inhibitory activities against PLCgamma1 in vitro with IC50 values ranging from 8.8 to 26.0 microM, the inhibition of PLCgamma1 may be an important mechanism for an antiproliferative effect on the human cancer cells, therefore, these inhibitors may be utilized as cancer chemotherapeutic and chemopreventive agents. 3. (-)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. | |
| BCN5516 | Cryptomeridiol |
| 1. (-)-Cryptomeridiol exhibits a significant and concentration-dependent inhibitory effect on PAF receptor binding, with inhibitory concentration (IC)(50) values of 17.5 uM. 2. Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. 3. Cryptomeridiol has low activity against A. niger, T. mentagrophytes, and C. albicans. | |
| BCN5517 | Nootkatone |
| Nootkatone, a naturally occurring AMPK activator, can stimulate energy metabolism and prevents diet-induced obesity by activating AMPK. (+)-Nootkatone has antiallergic, anti-inflammatory, antiproliferative, and antiplatelet activities. Nootkatone is a strong repellent and toxicant to Formosan subterranean termites, the lowest effective concentration tested is 10 micrograms/g substrate. (+)-Nootkatone has potent inhibitory effect on collagen-, thrombin-, and AA-induced platelet aggregation, it also has a significant inhibitory effect on rat platelet aggregation ex vivo. | |
