Products with Anti-platelet aggregation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6573 | 6-Deoxyjacareubin |
| 1. 6-Deoxyjacareubin, 1,5-dihydroxyxanthone, and 5-hydroxy-1-methoxyxanthoneis are antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B. 2. 6-Deoxyjacareubin shows strong platelet activating factor (PAF) receptor binding inhibitory effects using rabbit platelets with IC50 values of 29.0 microM, suggests that xanthones can represent a new class of natural PAF receptor antagonists. 3. 6-Deoxyjacareubin possesses significant antioxidant activities. 4. 6-Deoxyjacareubin exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines. | |
| BCN6578 | Piperenone |
| 1. Piperenone is an insect antifeeding substance. 2. Piperenone has anti-platelet-activating factor(PAF) activities, it is a PAF-acether antagonist. | |
| BCN6602 | Wallichinine |
| 1. Wallichinine shows inhibitory activity on platelet aggregation caused by platelet activating factor (PAF). 2. Wallichinine can significantly potentiate the effects of two ABCB1 substrates vincristine and doxorubicin on inhibition of growth, arrest of cell cycle and induction of apoptosis in ABCB1 overexpressing cancer cells, and the overexpression of ABCB1 in cancer cells is one of the main reasons of cancer multidrug resistance (MDR), suggests that wallichinine with ABCB1 presents valuable clues for the development of novel MDR reversal reagents from natural products. | |
| BCN6685 | Zanthobungeanine |
| 1. Zanthobungeanine shows the inhibitory action on the development of A549 cell only in high concentration and has no antipersonnel effect on A549 cell. 2. Zanthobungeanine has anti-inflammatory activity, it shows moderate NO production inhibitory activity with an IC50 value of 37.26 mg /L. 3. Zanthobungeanine shows obviously inhibitoryactivity to platelet aggregation caused by platelet-activating factor (PAF). | |
| BCN6723 | Xanthopurpurin |
| 1. Xanthopurpurin may can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. 2. Xanthopurpurin shows mainly strong inhibition of collagen-induced platelet aggregation. | |
