Products with Anti-platelet aggregation bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6313 | Proanthocyanidins |
| Proanthocyanidins exerts antiviral, hepatoprotective, cardioprotective, hypolipidemic, anti-osteoporosis, anti-inflammatory ,antioxidant and anti-apoptosis activities. Dietary proanthocyanidins inhibits photocarcinogenesis in mice through the inhibition of UVB-induced inflammation and mediators of inflammation in mouse skin. Proanthocyanidins form stable complexes with metal ions and with proteins and are good reducing agents, they may participate in the prevention of cancers, both of the digestive tract and inner organs, they may also protect LDLs against oxidation and inhibit platelet aggregation and therefore prevent cardiovascular diseases. | |
| BCN6345 | 3-Butylidenephthalide |
| (Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(50) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM. It can induce a dose-dependent antinociceptive action in the hot-plate assay, it is also effective for controlling the pain provoked by chemical irritation at the doses of 10 and 31.6 mg/kg. | |
| BCN6352 | Senkyunolide H |
| 1. Senkyunolide H, senkyunolide I and ferulic acid can reduce the metamorphose damage of the RBC caused by ConA, the aggregation of the RBC also could be alleviated by them. 2. Senkyunolide H in cnidium rhizome may be a prototype for an anti-atherosclerotic drug. | |
| BCN6408 | Futoenone |
| 1. Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases, the molecular modelings of these compounds indicate the preferred binding of the P2′ site of the enzymes. 2. Neolignan derivative compounds of the 2,4-diaryl-1,3-dithiolane and futoenone variety exhibit both platelet activating factor receptor(PAF)and 5-lipoxygenase antagonist activity. | |
| BCN6416 | Futoquinol |
| 1. Futoquinol can potently inhibit NO production with an IC(50) value of 16.8microM in microglia cells, suggests that it has anti-neuroinflammatory activities. 2. Futoquinol shows potent inhibition of PMA-induced ROS production in human polymorphonuclear neutrophils with IC(50) values 13.1 +/- 5.3 microM. 3. Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng. | |
