Products with Anti-platelet aggregation bioactivity

Cat.No. Product Name
BCN2648 Tetrahydroberberine
Tetrahydroberberine, with D(2) receptor antagonist and 5-HT(1A) receptor agonist properties, has significant potential as a therapeutic for treatment of FD; it has antidopaminergic effect, and other pharmacological action on the central nervous system. Tetrahydroberberine can inhibit the rabbit platelet aggregation.
BCN2650 Oxoglaucine
Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation activity against rabbit platelets induced by thrombin, arachidonic acid, collagen or platelet activating factor. Oxoglaucine and pachypodol are anti-picornavirus compounds, phosphatidylinositol 4-kinase III beta (PI4KB) as the direct target of them.
BCN2711 Selinidin
1. Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
BCN2799 Benzoyloxypeoniflorin
1. Benzoyloxypeoniflorin contributes to improving blood circulation through their inhibitory effects on both platelet aggregation and blood coagulation.
BCN2897 Soyasaponin Ac
1. Soyasaponins have chemoprevention activities, they prevent H2O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells. 2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis. 3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD). 4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice.

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