Products with Antifungal bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4690 | Goniothalamin |
| 1. Goniothalamin enhances rather than inhibits the ATPase activity of a cyanobacterial Hsp90 (HtpG) and a yeast Hsp90, increases both K(m) and k(cat) of the Hsp90s. 2. Goniothalamin induces oxidative stresses and inhibits the expression of cell wall-associated proteins resulting in growth inhibition of Arabidopsis seedlings. 3. Goniothalamin has gastroprotective activity which is inhibited after pre-treatment with NEM (N-ethylmaleimide) and NSAID (non-steroidal anti-inflammatory drugs), highlighting the importance of sulfhydryl compounds and prostaglandins on Goniothalamin activity. 4. Goniothalamin is a natural product that has been demonstrated to induce apoptosis in various cancer cell lines, can induce cytotoxicity and apoptosis on RT4 cells, induce apoptosis on HepG2 liver cancer cells via induction of caspase-3 with less sensitivity on the cell line of Chang cells. | |
| BCN4695 | Evofolin C |
| 1. Evofolin C and its acetate show strong antifungal and antibacterial activity. 2. Evofolin C exhibits potent inhibition against N-formylmethionylleucylphenylalanine-induced superoxide production with IC(50) values less than 12 microM. | |
| BCN4760 | Isoelemicin |
| BCN4818 | Piperolactam C |
| 1. Piperolactam C can inhibit the growth of the fungi Cladosporium sphaerospermum and C. cladosporioides. 2. Piperolactam C possesses anti-platelet aggregation activity in vitro. | |
| BCN4853 | Enniatin B1 |
| 1. Enniatin B1 has intestinal toxicity. 2. Enniatins A, A(1), B, B(1) have antifungal effects. 3. Enniatins A1, B and B1 induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. | |
