Products with Antifungal bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5459 | Nerolidol |
| Nerolidol, a sesquiterpene used as a food-flavoring agent and currently under testing as a skin penetration enhancer for the transdermal delivery of therapeutic drugs. Nerolidol shows anti-cancer, sedative, antiulcer, antifungal, and antifeeding effects. Nerolidol can inhibit the growth of Leishmania amazonensis, L. braziliensis, and L. chagasi promastigotes and L. amazonensis amastigotes with in vitro 50% inhibitory concentrations of 85, 74, 75, and 67 uM, respectively. | |
| BCN5462 | Medioresinol |
| 1. Medioresinol possesses a lesishmanicidal activity and cardiovascular disease risk reduction. 2.(+)-Medioresinol has anti-bacterial, antifungal and anti-biofilm activities. 3. Medioresinol has antioxidative activity. 4. Medioresinol has antiamyloidogenic activity via reduction in the amount of β-secretase, it is a potentially valuable antiamyloidogenic agent for the prevention and treatment of Alzheimer disease. | |
| BCN5476 | Luteone |
| 1.Luteone possesses antifungal activity sufficient to support its proposed role as pre-infectional resistance factors. | |
| BCN5516 | Cryptomeridiol |
| 1. (-)-Cryptomeridiol exhibits a significant and concentration-dependent inhibitory effect on PAF receptor binding, with inhibitory concentration (IC)(50) values of 17.5 uM. 2. Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. 3. Cryptomeridiol has low activity against A. niger, T. mentagrophytes, and C. albicans. | |
| BCN5532 | Liriodenine |
| 1. Liriodenine has antibacterial and antifungal activity. 2. Liriodenine inhibits progression of the CAOV-3 cell cycle in S phase. 3. Liriodenine exhibits potent antitumor activities in laryngocarcinoma HEp-2 cells, in vitro and in vivo, via the upregulation of p53 expression. 4. Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro. 5. Liriodenine can suppress ventricular arrhythmias induced by myocardial ischaemia reperfusion, through inhibition of Na+ and the Ito channel. 6. Liriodenine has antimuscarinic properties, the antimuscarinic characteristics are similar to those of 4-diphenylacetoxy-N-methylpiperidine (4-DAMP, smooth muscle selective M3 antagonist), it may act as a selective M3 receptor antagonist in canine tracheal smooth muscle. | |
