Products with Antifungal bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6076 | Coronarin D |
| 1. Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis. 2. Coronarin D is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases . 3. Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively. | |
| BCN6087 | Meridinol |
| 1. Meridinol has wide antimicrobial activity, includes against gram-positive and gram-negative bacteria and fungi. | |
| BCN6135 | Cedrelone |
| 1. Cedrelone exhibits antifeedant activity. 2. Cedrelone and its derivatives exert antimicrobial activities, bromohydroxy cedrelone and Michael adduct show good antifungal activity. 3. Cedrelone and dysobinin show significant cytotoxicity against cancer cell lines, such as -60, SMMC-7721, A-549, MCF-7 and SW480. 4. Cedrelone is a very potent inducers of apoptosis, it can cause cell cycle arrest. 5. Cedrelone has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fasciatus. | |
| BCN6214 | 3,4-Dihydroxybenzaldehyde |
| 3,4-Dihydroxybenzaldehyde, a potent tyrosinase inhibitor, has antifungal activity, it can inhibit oxidative DNA damage and apoptosis via its antioxidant activity. It inhibits the phosphotransferase activity of CKII with IC(50) of about 783 microM, it may function by inhibiting oncogenic disease, at least in part, through the inhibition of CKII activity. It inhibits the H2O2-induced apoptosis of granulosa cells, promotes estradiol secretion in granulosa cells and enhanced the mRNA expression levels of steroidogenic factor 1, a promoter of key steroidogenic enzymes. | |
| BCN6233 | Macrocarpal C |
| 1. Macrocarpal C, isolated from the fresh leaves of Eucalyptus globulus Labill. (Lan An) and identified as its major antifungal component by bioassay-guided purification, the antifungal action of macrocarpal C was associated with increases of membrane permeability, intracellular ROS and DNA fragmentation. | |
