Products with Antifungal bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5964 | Eugenol |
| Eugenol is an essential oil found in cloves with herbicide,sedative,analgesic,antibacterial,anthelmintic,anti-inflammatory, cancer chemopreventive and antioxidant activities. Eugenol is shown to inhibit lipid peroxidation, the mRNA expression of COX-2, but not COX-1 and inhibit the GABAA current in trigeminal ganglion neurons. It could be developed as therapeutic agent against diseases with excessive osteoclast activity. | |
| BCN6013 | Magnoloside A |
| Magnoloside A has potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 ug/ml. | |
| BCN6019 | Caryophyllene oxide |
| Caryophyllene oxide, an oxygenated terpenoid existed in many plant essential oil, is well known as preservative in food, drugs and cosmetics with antifungal, acaricidal, anti-inflammatory, anti-carcinogenic, significant central as well as peripheral analgesic and skin penetration enhancing properties. Caryophyllene Oxide and lupenone have synergistic effect against Trypanosoma cruzi. It inhibited growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways, ROS-mediated MAPKs activation, and via modulation of 15-LOX. | |
| BCN6036 | 2'-Hydroxygenistein |
| 1. 2'-Hydroxygenistein has antifungal activity, dimerization of it causes a remarkable increase of antifungal activity. 2. 2'-Hydroxygenistein exhibits greater antiproliferative effects in MCF-7 human breast cancer cells than does genistein, suggest that 2'-hydroxylation of genistein can enhance its antioxidant activity and cell cytotoxicity in MCF-7 human breast cancer cells. 3. 2'-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B. | |
| BCN6037 | Galanolactone |
| 1. Galanolactone shows cytotoxic activity . 2. Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors. 3. Galanolactone exerts anti-obesity effect through down regulation of adipogenic transcription factors and adipogenic marker genes. 4. Galanolactone has inhibit nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM. | |
