Products with Antifungal bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5160 | Ampelopsin |
| Ampelopsin,a major antifungal constituent from Salix sachalinensis, which has hepatoprotective, anti-inflammatory,antioxidant, antitumor, anti-invasive and anti-metastatic effects. It is an effective mTOR inhibitor, it inhibited the interconnected ROS/Akt/IKK/NF-κB signaling pathways, and it inhibited H₂O₂-induced apoptosis by ERK and Akt signaling pathways and up-regulation of heme oxygenase-1. | |
| BCN5194 | 5-Hydroxy-3',4',7-trimethoxyflavone |
| 5-Hydroxy-3',4',7-trimethoxyflavone has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug/ml. 5-Hydroxy-3',4',7-trimethoxyflavone shows prominent inhibitory activity against soybean lipoxygenase, it can significantly inhibit nitric oxide production and induce reduction in the mRNA expressions of inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide-induced inflammation in RAW 264.7 macrophages. | |
| BCN5217 | Corydalmine |
| 1. Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains. 2. 1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. 3. l-Corydalmine exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent. | |
| BCN5226 | Sideroxylin |
| 1. Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus by inhibition of the NorA multidrug resistance pump. | |
| BCN5238 | Methyl orsellinate |
| 1. Methyl orsellinate is a phytotoxic compound, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. 2. Methyl orsellinate exhibits antifungal activity. 3. Methyl orsellinate can inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM, the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity, methyl orsellinate may can treat the type 2 diabetes and obesity. | |
