Products with Antifungal bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4861 | 11-Hydroxytephrosin |
| 1. 11-Hydroxytephrosin inhibits NF-kappaB activity. | |
| BCN4883 | Isodiospyrin |
| 1. Isodiospyrin is a novel human DNA topoisomerase I inhibitor, it exhibits cytotoxic activity to tumor cell lines. 2. Isodiospyrin has antibacterial activity, the minimum inhibitory concentrations (MICs) against Gram-positive bacteria ranged from 0.78 to 50 microg/mL. 3. Isodiospyrin shows high antifungal activity against P. obscurans at 30uM with 81.4% growth inhibition, and moderate activity against P. viticola (36.6%). | |
| BCN4928 | Shoreic acid |
| 1. Shoreic acid shows activity against Mycobacterium tuberculosis. 2. Shoreic acid has antiviral activity against Herpes simplex virus types I and II in vitro. 3. Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albicans and T. mentagrophytes with AI of 0.2 and 0.3, respectively. | |
| BCN4955 | Isoalantolactone |
| Isoalantolactone, an apoptosis inducer, possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia. Isoalantolactone induces apoptosis, may be mediated through caspase-dependent apoptotic pathways, S phase arrest, inhibition of phosphorylation of PI3K/Akt, and downregulation of Bcr/Abl. | |
| BCN4976 | butanol |
| Tyrosol is a potential hypo-pigmenting agent, it has neuroprotective, antioxidant, anti-hyperglycemia, and anti-allergic inflammatory effects. Tyrosol has cytoprotective effect in I/R-caused myocyte mortality was involved with the mitigation of ROS, prohibition of the activation of ERK, JNK and caspase-8, and elevation of Hsp70 and Bcl-2/Bax ratio.Tyrosol is a quorum-sensing molecule in Candida albicans, it has important implications on the dynamics of growth and morphogenesis in Candida. | |
