Products with Antifungal bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6258 | Dihydropinosylvin |
| 1. Dihydropinosylvinin is an phytoalexin, it shows antifungal activity against Cladosporium cladosporioides, Botryodiplodia theobromae, Aspergillus niger and Penicillium schlerotgenum, it also exhibits strong antibacterial activity against Bacillus cereus, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. 2. Dihydropinosylvin and batatasin IV can inhibit the germination of seeds of and root elongation in young seedlings of Sorghum bicolor. | |
| BCN6283 | Amentoflavone |
| Amentoflavone is a novel natural inhibitor of human Cathepsin B(CatB), which has antifungal , antioxidant, antiviral, antidiabetic, and neuroprotective activities, it stimulates apoptosis in HSFBs and inhibits angiogenesis of endothelial cells, it is a promising molecule that can be used in hypertrophic scar treatment. Amentoflavone regulated β-catenin and caspase-3 expressions, and inhibited NF-κB signal transduction pathways. | |
| BCN6284 | Pseudolaric Acid B |
| Pseudolaric Acid B has dual antiangiogenic, anti-fungal, anti-fertility, anti-inflammatory, immunomodulatory and pro-apoptosis effects. Pseudolaric Acid B reversed the multidrug resistance of gastric neoplasm to chemotherapy drugs by downregulating the Cox-2/PKC-α/P-gp/mdr1 signaling pathway, it suppressed T lymphocyte activation through inhibition of NF-κB and p38 signaling pathways. | |
| BCN6292 | Atractylodin |
| Atractylodin has a good potential as a source for natural repellents, it could be developed as natural insecticide. Atractylodin has high lipase inhibitory activity with the IC50 of 39.12 μM. | |
| BCN6320 | Coptisine |
| Coptisine is an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM, it can consequently prevent neuron loss, reduce amyloid plaque formation, and ameliorate impaired cognition, it could as a potential new class of drugs for AD treatment. Coptisine has cardioprotection, anti- hypercholesterolemia, anti-fungal, anti-osteosarcoma, anti-hepatoma and anti-leukaemia activities, it also has antispasmodic and relaxant activity on a guinea-pig ileum. | |
