Products with Antiviral bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1708 | Catalpalactone |
| 1. Catalpalactone can inhibit dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities and enhance L-DOPA- induced cytotoxiciy in PC12 cells. 2. Catalpalactone displays good cytotoxicity activities against two human tumor cell lines(MCF-7,BxPC3). 3. Catalpalactone exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells. 4. Catapalactone exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. 5. Catalpalactone exhibits high antitermitic activity. | |
| BCN1710 | 3',5,5',7-Tetrahydroxyflavanone |
| 1. 5,7,3',5'-Tetrahydroxyflavanone has inhibitory effects on HIV-1 reverse transcriptase (RT)-associated RNase H function, it may have antiviral activity against HIV-1. 2. 5,7,3',5'-Tetrahydroxyflavanone has anti-inflammatory properties, it can inhibit nitric oxide (NO) production with IC50 values of 18.5 uM, the inhibitory effect is accompanied by dose-dependent decreases in LPS-induced nitric oxide synthase (iNOS) in RAW 264.7 cells. | |
| BCN1849 | Oteromycin |
| 1. Oteromycin is a inhibitor of HIV-1 integrase. | |
| BCN1977 | Europine N-oxide |
| 1. Supinine, lasiocarpine-N-oxide and Europine N-oxide exhibit virucidal activity to Poliomyelitis, Coxsackie, Semliki forest, Vesicular stomatitis and Herpes simplex at the concentration of 5, 10 and 20 mu g/ml respectively. | |
| BCN2178 | Tenofovir disoproxil |
| 1. Tenofovir disoproxil fumarate monotherapy is superior to continuous add-on therapy in patients with LAM-resistant CHB with a suboptimal response to LAM plus ADV. 2. Tenofovir disoproxil has anti-HIV-1 activity. | |
