Products with Lung protection Bioactivity

Explore BioCrick products associated with Lung protection biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN5774	Liriodendrin
1. Liriodendrin has anti-inflammatory and antinociceptive activities. 2. Liriodendrin shows an excellent hypoglycemic activity. 3. Liriodendrin has protective effects on dopamine-induced cytotoxicity via its anti-oxidative properties by reducing ROS level and anti-apoptotic effect via protection of mitochondrion membrane potential (ΔΨm). 4. Liriodendrin may be a potent suppressor of CaCl(2)-induced arrhythmias, the prophylactic administration of liriodendrin is effective in prolonging latency of arrhythmia and reducing the occurrence of ventricular fibrillation from 75% to 25%. 5. Liriodendrin has inhibitory activities on gastritis and gastric ulcer, it can inhibit colonization of Helicobacter pylori effectively, it could be utilized for the treatment and/or protection of gastritis and gastric ulcer. 6. Liriodendrin plays protective role in sepsis-induced acute lung injury, it regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF).
BCN5793	Dihydroresveratrol
Dihydroresveratrol has antiproliferative activity against human prostate cancer PC3 cell line in vitro, it can ameliorate acute pancreatitis-associated lung injury via an inhibitory modulation of pro-inflammatory response, which is associated with a suppression of the NF-κB signaling pathway.
BCN6239	Neotuberostemonine
1. Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. 2. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
BCN6338	Neferine
Neferine, a autophagy inducer, which has anti-amnesic, sedative, anti-anxiety, antidepressant, cardioprotective, anti- pulmonary fibrosis,anti-cancer, antioxidant and anti-inflammatory capacities. It inhibited ChEs, BACE1, NF-kappaB, PI3K/Akt/mTOR pathway, Neferine has effects similar to rosiglitazone in decreasing fasting blood glucose, insulin, TG, TNF-alpha and enhancing insulin sensitivity in insulin resistant rats.
BCN6569	1-Hydroxy-2,3,5-trimethoxyxanthone
1. 1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type voltage-operated Ca(2+) channels; a minor contribution to the effects of HM-1 may be related to inhibition of the protein kinase C-mediated release of intracellular Ca(2+) stores. 2. HM-1,at the concentration of 1 ug/mL, can effectively inhibit the osteoclast differentiation in a co-culture system with mouse osteoblastic calvarial cells and bone marrow cells, it exhibits significant inhibition of osteoclast differentiation even at a low concentration (0.01 ug/mL) in a dose-dependent manner, and it can significantly reduce the pit formation on the dentine slice compared with the control group. 3. HM-1 can protect mice from the acute lung injury induced by ipopolysaccharide (LPS), which is relative to the increasing of IκB-α protein expression and the suppressing of inducible nitric oxide synthase and cyclooxygenase-Ⅱ protein expression.

Lung protection Bioactivity Products