Products with Neuroprotection Bioactivity

Explore BioCrick products associated with Neuroprotection biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN2741	Onjisaponin B
Onjisaponin B induces autophagy via the AMPK-mTOR signaling pathway, increases the NGF level and accelerates both the removal of mutant huntingtin and A53T α-synuclein, it may have potential therapeutic effects on Parkinson disease, Alzheimer disease and Huntington disease. Onjisaponins may provide safe and potent adjuvants for intranasal inoculation of influenza HA and DPT vaccines.
BCN2744	Sarcosine
Sarcosine is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist, it preconditioning induces ischemic tolerance against global cerebral ischemia and this neuroprotective state is associated with changes in glycine transport and reduction of NR2B-containing NMDAR expression.Sarcosine modulates endothelial cell function relevant to angiogenesis through modulation of PI3K/Akt/mTOR pathway.
BCN2756	Hirsuteine
Hirsuteine exhibits potent neuroprotective effects against glutamate-induced HT22 cell death. Hirsuteine non-competitively antagonizes nicotine-evoked dopamine release by blocking ion permeation through nicotinic receptor channel complexes.
BCN2758	Hirsutine
Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity.
BCN2762	Swertisin
Swertisin, a novel herbal biomolecule, shows a strong antihyperglycemic action, it provides low cost and readily available differentiating agent that can be translated as a therapeutic tool for effective treatment in diabetes.

Neuroprotection Bioactivity Products