Products with Neuroprotection Bioactivity

Explore BioCrick products associated with Neuroprotection biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN3037	Ganoderic acid F
Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.
BCN3149	Quercetin-3-O-glucuronide
Quercetin-3-O-glucuronide is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. Quercetin-3-O-glucuronide significantly improves Alzheimer's disease (AD)-type deficits in hippocampal formation basal synaptic transmission and long-term potentiation, possibly through mechanisms involving the activation of the c-Jun N-terminal kinases and the mitogen-activated protein kinase signaling pathways. Quercetin-3-O-glucuronide is equally effective in inhibiting ROS-associated inflammation and ameliorating insulin resistant endothelial dysfunction by beneficial regulation of IRS-1 function.
BCN3262	Chebulagic acid
Chebulagic acid is a potent DNA topoisomerase inhibitor, and is also COX-2 and 5-LOX dual inhibitor. Chebulagic acid may be of value as broad-spectrum antivirals for limiting emerging/ recurring viruses known to engage host cell glycosaminoglycans for entry. Chebulagic acid can be used to control blood glucose and manage type 2 diabetes, although clinical trials are needed.
BCN3308	Leachianone G
1. Leachianone G shows inhibitory activities against pancreatic lipase, it may be used as drug candidate to control obesity. 2. (+/-)Leachianone G 1b, bearing 8-prenyl and 2',4'-dihydoxyl groups, exhibits potent vasorelaxant and neuroprotective effects. 3. Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays. 4. Leachianone G shows potent antiviral activity (IC(50) = 1.6 microg/ml).
BCN3316	Schisandrone
1. Schisandrone can suppress the Aβ-induced oxidative stress and inflammatory reaction through influencing NF-κB signaling pathway, exerting its protective effect on Alzheimer disease. 2. Schisandrone has strong activities of anti-oxidation, effectively scavenges hydroxyl radical and superoxide anion, and has protective effects on cells under active oxygen stress state. 3. Schisandrone can significantly decrease phosphorylation levels of Tau protein at 396, 262 sites, and relieve neuronal injury, but the phosphorylation level does not reach a negative cell level.

Neuroprotection Bioactivity Products