Products with Neuroprotection bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3836 | Kukoamine B |
| 1. Kukoamine B is a potent dual inhibitor for both Lipopolysaccharides (LPS) and oligodeoxynucleotides containing CpG motifs (CpG DNA), LPS and CpG DNA are important pathogenic molecules for the induction of sepsis,are drug targets for sepsis treatment, thus kukoamine B is worthy of further investigation as a potential candidate to treat sepsis. 2. Kukoamine B inhibits inflammation in septic mice by reducing the concentrations of plasma LPS, decreasing leukocyte sequestration and interfering with NFκB activation, and, therefore, suppressing the proadhesive phenotype of endothelial cells. 3. Kukoamine B has protective effects against hydrogen peroxide (H2O2) induced cell injury and potential mechanisms in SH-SY5Y cells, it may potentially serve as an agent for prevention of several human neurodegenerative and other disorders caused by oxidative stress. | |
| BCN3837 | alpha-Asarone |
| 1. Alpha-Asarone shows insecticidal activity. | |
| BCN3841 | Inosine |
| Inosine, an endogenous purine nucleoside, has immunomodulatory, neuroprotective, and analgesic properties.Inosine is a cardiotonic agent, can treat cardiac disorders.Inosine can to be capable of forming base pairs with Adenine HFN72-P, Cytosine HDR44-O or Uracil BTP40-U thus contributing to genetic code degeneracy by causing stable mispairings. | |
| BCN3854 | Notoginsenoside Fa |
| Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells. | |
| BCN3936 | Obtucarbamate A |
| 1. Obtucarbamate A has antitussive activity. 2. Obtucarbamate A exhibits significant inhibitory effect against neuroinflammation with the IC50 value of 10.57 uM . | |
