Products with Neuroprotection bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4406 | Curculigoside |
| Curculigoside has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effects. Curculigoside can improve cognitive function in aged animals, possibly by decreasing the activity of AchE in the cerebra and inhibiting the expression of BACE1 in the hippocampus. Curculigoside exhibits potent inhibitory activity against matrix metalloproteinase-1 in cultured human skin fibroblasts, and increases the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. | |
| BCN4414 | Clausine Z |
| 1. Clausine Z exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro. | |
| BCN4450 | Neochlorogenic acid |
| Neochlorogenic acid shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia. | |
| BCN4537 | 3,4-Dihydroxybenzoic acid |
| 3,4-Dihydroxybenzoic acid shows significant nematicidal, antitumor, neuroprotective, antioxidant, and antimicrobial activities. 3,4-Dihydroxybenzoic acid has protection against adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity; it also protects human keratinocytes against UVB-induced oxidative stress and apoptosis.3,4-Dihydroxybenzoic acid can prevent Abeta (25-35)-induced neuronal cell damage by interfering with the increase of [Ca(2+)](c), and then by inhibiting glutamate release, generation of ROS and caspase-3 activity. | |
| BCN4571 | Grossamide |
| Grossamide possesses potential anti-inflammatory effects, it also has potential anti-neuroinflammatory effects against lipopolysaccharide (LPS)-induced inflammatory response in BV2 microglia cells. Cis-Grossamide K exerts a particularly strong anti-melanogenic activity on the cells without high cell toxicity. | |
