Clausine ZCAS# 866111-14-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 866111-14-0 | SDF | Download SDF |
PubChem ID | 11436094 | Appearance | Powder |
Formula | C13H9NO3 | M.Wt | 227.2 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 1,6-dihydroxy-9H-carbazole-3-carbaldehyde | ||
SMILES | C1=CC2=C(C=C1O)C3=CC(=CC(=C3N2)O)C=O | ||
Standard InChIKey | FKDULSCBYNXNMP-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C13H9NO3/c15-6-7-3-10-9-5-8(16)1-2-11(9)14-13(10)12(17)4-7/h1-6,14,16-17H | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
The herbs of Clausena excavata
Description | 1. Clausine Z exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro. |
Targets | CDK |
Clausine Z Dilution Calculator
Clausine Z Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 4.4014 mL | 22.007 mL | 44.0141 mL | 88.0282 mL | 110.0352 mL |
5 mM | 0.8803 mL | 4.4014 mL | 8.8028 mL | 17.6056 mL | 22.007 mL |
10 mM | 0.4401 mL | 2.2007 mL | 4.4014 mL | 8.8028 mL | 11.0035 mL |
50 mM | 0.088 mL | 0.4401 mL | 0.8803 mL | 1.7606 mL | 2.2007 mL |
100 mM | 0.044 mL | 0.2201 mL | 0.4401 mL | 0.8803 mL | 1.1004 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- 6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane
Catalog No.:BCN1326
CAS No.:86606-14-6
- L-745,870 trihydrochloride
Catalog No.:BCC5695
CAS No.:866021-03-6
- Oleuropeic acid 8-O-glucoside
Catalog No.:BCN4025
CAS No.:865887-46-3
- Tideglusib
Catalog No.:BCC4511
CAS No.:865854-05-3
- Isochamaejasmenin B
Catalog No.:BCN3045
CAS No.:865852-48-8
- Chamaejasmenin D
Catalog No.:BCN3046
CAS No.:865852-47-7
- RX-3117
Catalog No.:BCC6381
CAS No.:865838-26-2
- Cytochrome c - pigeon (88-104)
Catalog No.:BCC1038
CAS No.:86579-06-8
- PF-03084014
Catalog No.:BCC1848
CAS No.:865773-15-5
- Trelagliptin
Catalog No.:BCC2014
CAS No.:865759-25-7
- 2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]benzonitrile
Catalog No.:BCC8506
CAS No.:865758-96-9
- TC-E 5001
Catalog No.:BCC6355
CAS No.:865565-29-3
New Products
- PRX-08066
Catalog No.:BCC4209
CAS No.:866206-54-4
- PRX-08066 Maleic acid
Catalog No.:BCC1165
CAS No.:866206-55-5
- 3,4,5-Tricaffeoylquinic acid
Catalog No.:BCN2384
CAS No.:86632-03-3
- Xanthiside
Catalog No.:BCN2545
CAS No.:866366-86-1
- 7-Ethyl-10-Hydroxycamptothecin
Catalog No.:BCN2479
CAS No.:86639-52-3
- 10-Aminocamptothecin
Catalog No.:BCC8111
CAS No.:86639-63-6
- DPPI 1c hydrochloride
Catalog No.:BCC2363
CAS No.:866396-34-1
- Dorsomorphin
Catalog No.:BCC5131
CAS No.:866405-64-3
- 7-Hydroxy-3-prenylcoumarin
Catalog No.:BCN4415
CAS No.:86654-26-4
- [Ala2,8,9,11,19,22,24,25,27,28]-VIP
Catalog No.:BCC5973
CAS No.:866552-34-3
- Yuexiandajisu D
Catalog No.:BCN3774
CAS No.:866556-15-2
- Yuexiandajisu E
Catalog No.:BCN3775
CAS No.:866556-16-3
Clausine Z, a new carbazole alkaloid from Clausena excavata with inhibitory activity on CDK5.[Pubmed:16124414]
Pharmazie. 2005 Aug;60(8):637-9.
A new carbazole alkaloid, named Clausine Z, has been isolated from the stems and leaves of Clausena excavata Burm. (Rutaceae). Its structure was established by spectroscopic methods. The compound exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro.
Clausine Z,866111-14-0,Natural Products, buy Clausine Z , Clausine Z supplier , purchase Clausine Z , Clausine Z cost , Clausine Z manufacturer , order Clausine Z , high purity Clausine Z