DPPI 1c hydrochlorideDPP-IV Inhibitor CAS# 866396-34-1 |
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Quality Control & MSDS
3D structure
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| Cas No. | 866396-34-1 | SDF | Download SDF |
| PubChem ID | 11381416 | Appearance | Powder |
| Formula | C14H20N4O2 | M.Wt | 276.3 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in DMSO > 10 mM | ||
| Chemical Name | (2R,5S)-1-[2-[[1-(hydroxymethyl)cyclopentyl]amino]acetyl]pyrrolidine-2,5-dicarbonitrile | ||
| SMILES | C1CCC(C1)(CO)NCC(=O)N2C(CCC2C#N)C#N | ||
| Standard InChIKey | VZOVKVCGZDERPK-TXEJJXNPSA-N | ||
| Standard InChI | InChI=1S/C14H20N4O2/c15-7-11-3-4-12(8-16)18(11)13(20)9-17-14(10-19)5-1-2-6-14/h11-12,17,19H,1-6,9-10H2/t11-,12+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
DPPI 1c hydrochloride Dilution Calculator
DPPI 1c hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.6193 mL | 18.0963 mL | 36.1925 mL | 72.3851 mL | 90.4814 mL |
| 5 mM | 0.7239 mL | 3.6193 mL | 7.2385 mL | 14.477 mL | 18.0963 mL |
| 10 mM | 0.3619 mL | 1.8096 mL | 3.6193 mL | 7.2385 mL | 9.0481 mL |
| 50 mM | 0.0724 mL | 0.3619 mL | 0.7239 mL | 1.4477 mL | 1.8096 mL |
| 100 mM | 0.0362 mL | 0.181 mL | 0.3619 mL | 0.7239 mL | 0.9048 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 = 104 nM) that displays selectivity over enzymes with DPP-like activity (IC50 > 30 μM). Increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge.
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