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Officinalisinin I

CAS# 57944-18-0

Officinalisinin I

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Quality Control of Officinalisinin I

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Chemical structure

Officinalisinin I

3D structure

Chemical Properties of Officinalisinin I

Cas No. 57944-18-0 SDF Download SDF
PubChem ID 441889 Appearance Powder
Formula C45H76O19 M.Wt 921.07
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1C2C(CC3C2(CCC4C3CCC5C4(CCC(C5)OC6C(C(C(C(O6)CO)O)O)OC7C(C(C(C(O7)CO)O)O)O)C)C)OC1(CCC(C)COC8C(C(C(C(O8)CO)O)O)O)O
Standard InChIKey SORUXVRKWOHYEO-YGNOLRTQSA-N
Standard InChI InChI=1S/C45H76O19/c1-19(18-58-40-37(55)34(52)31(49)27(15-46)60-40)7-12-45(57)20(2)30-26(64-45)14-25-23-6-5-21-13-22(8-10-43(21,3)24(23)9-11-44(25,30)4)59-42-39(36(54)33(51)29(17-48)62-42)63-41-38(56)35(53)32(50)28(16-47)61-41/h19-42,46-57H,5-18H2,1-4H3/t19-,20+,21-,22+,23-,24+,25+,26+,27-,28-,29-,30+,31-,32-,33-,34+,35+,36+,37-,38-,39-,40-,41+,42-,43+,44+,45-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Officinalisinin I

The rhizomes of Anemarrhena asphodeloides Bunge

Biological Activity of Officinalisinin I

Description1. Officinalisinin Ⅰ can effectively reduce the blood glucose and protect nerve injuryin diabetic mice.

Officinalisinin I Dilution Calculator

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Officinalisinin I Molarity Calculator

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Preparing Stock Solutions of Officinalisinin I

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0857 mL 5.4285 mL 10.8569 mL 21.7139 mL 27.1423 mL
5 mM 0.2171 mL 1.0857 mL 2.1714 mL 4.3428 mL 5.4285 mL
10 mM 0.1086 mL 0.5428 mL 1.0857 mL 2.1714 mL 2.7142 mL
50 mM 0.0217 mL 0.1086 mL 0.2171 mL 0.4343 mL 0.5428 mL
100 mM 0.0109 mL 0.0543 mL 0.1086 mL 0.2171 mL 0.2714 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Officinalisinin I

[Quality Analysis and Evaluation of Anemarrhena asphodeloides Rhizome from Different Habitats].[Pubmed:26762052]

Zhong Yao Cai. 2015 Jun;38(6):1148-52.

UNLABELLED: tive: To compare and analyze the quality of Anemarrhena asphodeloides rhizome from different habitats. METHODS: Simultaneous determination of nine components in Anemarrhena asphodeloides rhizome by UPLC-TQ/MS was performed on a Phenomenex Kinetex XB-C18 (100 mm x 2.1 mm, 1.7 mum) column with the mobile phase consisted of 0.1% formic acid-acetonitrile (gradient elution) at the flow rate of 0.4 mL/min and thecolumn temperature at 35 degrees C. Multiple reaction mode detection (MRM) in mode was used in this assay. RESULTS: Nine components were separated totally within 15 min. Good correlation were found between the investigated compounds concentrations and their peak areas within the test ranges with the correlation coefficient from 0.9917 to 0.9992. The average recoveries were from 98.1% to 103.7%, and the RSD of precision was in the range of 1.7% - 4.7%. 0.074-3.620 mg/g for sarsasapogenin, 0.042-2.530 mg/g for timosaponin A III, 22.1- 50.4 mg/g for timosaponon B II, 0.10 -8.28 mg/g for Officinalisinin II, 0.64 -7.29 mg/g for anemarsaponin B III, 3.28 -27.40 mg/g for mangiferin, 1.83 - 7.21 mg/g for isomangiferin, 0.36 -9.25 mg/g for neomangiferin and 4.72 x 10(-5) - 1.38 x 10(-3) mg/g for baohuoside I in Anemarrhena asphodeloides rhizome from different habitats were detected. CONCLUSION: The method is rapid, accurate and can be used for quality evaluation of Anemarrhena asphodeloides rhizome. The quality of Anemarrhena asphodeloides rhizome from different habitats are different. The saponins content of Anemarrhena asphodeloides rhizome in Hebei is higher than that of the others.

Description

Officinalisinin I is a steroidal saponin, isolated from Anemarrhena asphodeloides.

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