Anemarsaponin BIIICAS# 142759-74-8 |
- Anemarsaponin B
Catalog No.:BCN6289
CAS No.:139051-27-7
- Timorsaponin C
Catalog No.:BCN2899
CAS No.:185432-00-2
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 142759-74-8 | SDF | Download SDF |
| PubChem ID | 192323 | Appearance | Powder |
| Formula | C45H74O18 | M.Wt | 903.1 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1=C(OC2C1C3(CCC4C(C3C2)CCC5C4(CCC(C5)OC6C(C(C(C(O6)CO)O)O)OC7C(C(C(C(O7)CO)O)O)O)C)C)CCC(C)COC8C(C(C(C(O8)CO)O)O)O | ||
| Standard InChIKey | ROHLIYKWVMBBFX-GFMVILKCSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Structure Identification | Molecules, 2015, 20(4):6700-14.Simultaneous Determination of Five Components in Rat Plasma by UPLC–MS/MS and Its Application to a Comparative Pharmacokinetic Study in Baihe Zhimu Tang and Zhimu Extract.[Reference: WebLink]Baihe Zhimu Tang (BZT) is a famous traditional Chinese medicine recipe to treat dry coughing due to yin deficiency and for moisturizing the lungs. Zhimu is an essential ingredient in BZT used to treat inflammation, fever and diabetes. The most important active components in Zhimu are flavonoids such as neomangiferin, mangiferin, and steroid saponins (e.g., timosaponin BII, Anemarsaponin BIII, timosaponin AIII).
|
Anemarsaponin BIII Dilution Calculator
Anemarsaponin BIII Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.1073 mL | 5.5365 mL | 11.073 mL | 22.1459 mL | 27.6824 mL |
| 5 mM | 0.2215 mL | 1.1073 mL | 2.2146 mL | 4.4292 mL | 5.5365 mL |
| 10 mM | 0.1107 mL | 0.5536 mL | 1.1073 mL | 2.2146 mL | 2.7682 mL |
| 50 mM | 0.0221 mL | 0.1107 mL | 0.2215 mL | 0.4429 mL | 0.5536 mL |
| 100 mM | 0.0111 mL | 0.0554 mL | 0.1107 mL | 0.2215 mL | 0.2768 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Buddlenoid A
Catalog No.:BCN8210
CAS No.:142750-32-1
- Conophylline
Catalog No.:BCN6237
CAS No.:142741-24-0
- FGIN-1-27
Catalog No.:BCC6738
CAS No.:142720-24-9
- Dihydrocurcumenone
Catalog No.:BCN3557
CAS No.:142717-57-5
- CP 100356 hydrochloride
Catalog No.:BCC7882
CAS No.:142715-48-8
- Macrocarpal B
Catalog No.:BCN6236
CAS No.:142698-60-0
- Genkwanol B
Catalog No.:BCN8013
CAS No.:142674-67-7
- 6-Hydroxykaempferol 3,6-diglucoside
Catalog No.:BCN3335
CAS No.:142674-16-6
- Macrocarpal D
Catalog No.:BCN6235
CAS No.:142647-71-0
- Macrocarpal E
Catalog No.:BCN6234
CAS No.:142628-54-4
- Macrocarpal C
Catalog No.:BCN6233
CAS No.:142628-53-3
- Daphylloside
Catalog No.:BCN6232
CAS No.:14260-99-2
- 12-Hydroxysapriparaquinone
Catalog No.:BCN3216
CAS No.:142763-37-9
- Domoic acid
Catalog No.:BCC6586
CAS No.:14277-97-5
- IWP-L6
Catalog No.:BCC5101
CAS No.:1427782-89-5
- 4-Chlorophenylguanidine hydrochloride
Catalog No.:BCC2382
CAS No.:14279-91-5
- Silybin B
Catalog No.:BCN7898
CAS No.:142797-34-0
- 5,7-Dimethoxyluteolin
Catalog No.:BCN8167
CAS No.:90363-40-9
- DPN
Catalog No.:BCC7088
CAS No.:1428-67-7
- Apiodionene
Catalog No.:BCN1829
CAS No.:142808-38-6
- Preapiodionene
Catalog No.:BCN1854
CAS No.:142808-39-7
- Clinopodiside A
Catalog No.:BCN2621
CAS No.:142809-89-0
- L-Sulforaphane
Catalog No.:BCN8449
CAS No.:142825-10-3
- Clausine D
Catalog No.:BCN4707
CAS No.:142846-95-5
Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat.[Pubmed:26132904]
Molecules. 2015 Jun 26;20(7):11777-92.
A rapid, selective and sensitive UPLC-MS/MS assay was established to determine the plasma concentrations of four steroidal saponins. Sprague-Dawley rats were allocated to four groups which were orally administered Anemarrhena asphodeloides extracts (ASE), ASE combined with macromolecular fraction (ASE-MF), ASE combined with small molecule fraction (ASE-SF) and ASE combined with small molecule and macromolecular fraction (ASE-SF-MF) containing approximately the same dose of ASE. At different time points, the concentration of timosaponin BII, Anemarsaponin BIII, timosaponin AIII and timosaponin E1 in rat plasma were determined and main pharmacokinetic parameters including Cmax, Tmax, T1/2, AUC were calculated using the DAS 3.2 software package. The statistical analysis was performed using the Student's t-test with p < 0.05 as the level of significance. MF had no effect on the pharmacokinetic behaviors and parameters of four steroidal saponins. It was found that Cmax and AUC of four steroidal saponins in group ASE-SF and ASE-SF-MF, were significantly increased compared with those in group ASE. These results indicate that SF in A. asphodeloides extracts could increase the absorption and improve the bioavailability of the steroidal saponins.
Simultaneous determination of five components in rat plasma by UPLC-MS/MS and its application to a comparative pharmacokinetic study in Baihe Zhimu Tang and Zhimu extract.[Pubmed:25884551]
Molecules. 2015 Apr 15;20(4):6700-14.
Baihe Zhimu Tang (BZT) is a famous traditional Chinese medicine recipe to treat dry coughing due to yin deficiency and for moisturizing the lungs. Zhimu is an essential ingredient in BZT used to treat inflammation, fever and diabetes. The most important active components in Zhimu are flavonoids such as neomangiferin, mangiferin, and steroid saponins (e.g., timosaponin BII, Anemarsaponin BIII, timosaponin AIII). The aim of this study was to compare the pharmacokinetics of mangiferin, neomangiferin, timosaponin BII, Anemarsaponin BIII and timosaponin AIII in rat plasma after oral administration of BZT and Zhimu extract (ZME). A sensitive, reliable and robust LC-MS/MS method to simultaneously determine steroid saponins and flavonoids in rat plasma was successfully validated. Significant differences (p < 0.05) were found in the pharmacokinetic parameters of timosaponin BII, Anemarsaponin BIII and timosaponin AIII between BZT and ZME. It was surmised that formula compatibility could significantly influence the pharmacokinetics of BZT and our study is the first to study the administration of BZT based on pharmacokinetic studies.
