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12-Hydroxysapriparaquinone

CAS# 142763-37-9

12-Hydroxysapriparaquinone

2D Structure

Catalog No. BCN3216----Order now to get a substantial discount!

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12-Hydroxysapriparaquinone: 5mg $748 In Stock
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Quality Control of 12-Hydroxysapriparaquinone

3D structure

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12-Hydroxysapriparaquinone

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Chemical Properties of 12-Hydroxysapriparaquinone

Cas No. 142763-37-9 SDF Download SDF
PubChem ID 369176 Appearance Powder
Formula C20H24O3 M.Wt 312.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-hydroxy-7-methyl-8-(4-methylpent-3-enyl)-3-propan-2-ylnaphthalene-1,2-dione
SMILES CC1=C(C2=C(C=C1)C(=C(C(=O)C2=O)C(C)C)O)CCC=C(C)C
Standard InChIKey BLUCWOJJYVHVNH-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 12-Hydroxysapriparaquinone

The roots of Salvia prionitis

Biological Activity of 12-Hydroxysapriparaquinone

Description12-Hydroxysapriparaquinone is a natural product from Salvia prionitis.
In vivo

Biological activity of diterpenoids isolated from Anatolian Lamiaceae Plants[Reference: WebLink]

Records of Natural Products, 2007 , 1 (1) :1-16.


METHODS AND RESULTS:
Since Salvia species, especially Chinese sage S. milthiorrhiza has been used in the treatment of coronary heart diseases, Prof. Ulubelen group also investigated cardiovascular properties of several Salvia extracts (S. amplexicaulis, S. eriophora and S. syriaca) and their constituents in vivo, on Wistar Albino rats [5, 40-42]. The crude extract of S. eriophora and isolated eleven diterpenoids ferruginol (11), aethiopinone (56), 4,12-dihydroxysapriparaquinone (63), 6,7-didehydroroyleanone (64) and 4,14-dihydroxysaprorthoquinone (65), horminone, acetylhorminone, salvipisone, 12-Hydroxysapriparaquinone, 3,12-dihydroxysapri-paraquinone-1-ene, salvilimbinol, were tested [40] for cardiovascular activity.
CONCLUSIONS:
Among the tested abietanes, compounds 65, 56, 11, 63 and 64 as well as the crude extract showed antihypertensive activity, especially ferruginol, aethiopinone and 4,12- dihydroxysapriparaquinone by significantly reducing arterial blood pressure, and this activity is considered probably due to the vasorelaxation activity [5].

12-Hydroxysapriparaquinone Dilution Calculator

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12-Hydroxysapriparaquinone Molarity Calculator

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Preparing Stock Solutions of 12-Hydroxysapriparaquinone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.201 mL 16.0051 mL 32.0102 mL 64.0205 mL 80.0256 mL
5 mM 0.6402 mL 3.201 mL 6.402 mL 12.8041 mL 16.0051 mL
10 mM 0.3201 mL 1.6005 mL 3.201 mL 6.402 mL 8.0026 mL
50 mM 0.064 mL 0.3201 mL 0.6402 mL 1.2804 mL 1.6005 mL
100 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6402 mL 0.8003 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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