Products with Toxicity bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6263 | Aristolochic acid B |
| Aristolochic acid II (Aristolochic acid B，AAII), one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, AAII shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma. | |
| BCN6315 | Procyanidin B2 |
| Procyanidin B2 has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway, and up-regulated the expression of GSTP1 via a mechanism that involves ERK and p38 MAPK activation and Nrf2 translocation. It has anti- and pro-oxidant effects on metal-mediated DNA damage by interacting with H2O2 and metal ions. | |
| BCN6726 | Cauloside A |
| 1. Cauloside A exhibits concentration- and time-dependent mitochondriotoxic activities. | |
| BCN6745 | Victoxinine |
| 1. Victoxinine, the toxic metabolite, considered previously to be a unique product of Helminthosporium victoriae. | |
| BCN6797 | 4-(4-Hydroxyphenyl)-2-butanone |
| Raspberry ketone prevents and improves obesity and fatty liver by increasing norepinephrine-induced lipolysis in white adipocytes, it also can increase the fatty acid oxidation and suppressed lipid accumulation in 3T3-L1 adipocytes. Raspberry ketone has anti-melanogenic activity, it could be used to treat hyperpigmentation. Raspberry ketone enhances the differentiation of C3H10T1/2 stem cells into osteoblasts, and it may promote bone formation by an action unrelated to adipocyte differentiation. | |
