Salvia miltiorrhiza
Salvia miltiorrhiza
1. The products in our compound library are selected from thousands of unique natural products; 2. It has the characteristics of diverse structure, diverse sources and wide coverage of activities; 3. Provide information on the activity of products from major journals, patents and research reports around the world, providing theoretical direction and research basis for further research and screening; 4. Free combination according to the type, source, target and disease of natural product; 5. The compound powder is placed in a covered tube and then discharged into a 10 x 10 cryostat; 6. Transport in ice pack or dry ice pack. Please store it at -20 °C as soon as possible after receiving the product, and use it as soon as possible after opening.
Natural products/compounds from Salvia miltiorrhiza
- Cat.No. Product Name CAS Number COA
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BCN2824
9'-Methyl lithospermate B1167424-31-8
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BCN2923
9'''-Methyl salvianolate B1167424-32-9
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BCC8249
Salvianolic acid B; Lithospermic acid B; Danfensuan B121521-90-2
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BCN2925
Przewalskinic acid A136112-75-9
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BCN6214
3,4-Dihydroxybenzaldehyde139-85-5
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BCN2924
Salvianolic acid F158732-59-3
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BCN5893
Rosmarinic acid20283-92-5
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BCN5369
Lithospermic acid28831-65-4
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BCN4983
Crotaline315-22-0
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BCN5979
Caffeic acid331-39-5
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BCN5304
Cryptotanshinone35825-57-1
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BCN2386
Tangeretin481-53-8
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BCN5653
Kaempferol520-18-3
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BCN5763
Tanshinone IIA568-72-9
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BCN5764
Tanshinone I568-73-0
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BCN4169
Neoprzewaquinone A630057-39-5
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BCN6271
Colchicine64-86-8
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BCN5952
Sodium Danshensu67920-52-9
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BCN8513
Danshensu76822-21-4
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BCN4417
Dihydrotanshinone I87205-99-0
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BCN2823
Dimethyl lithospermate B875313-64-7
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BCN5951
Salvianolic acid A96574-01-5
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Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cells.[Pubmed: 30094960]
Ovarian cancer is the most malignant gynecologic cancer among women worldwide. Cryptotanshinone (CT), isolated from Salvia miltiorrhiza Bunge, has been identified as a potential therapeutic agent in treating several malignant tumors, but the molecular mechanism of CT in ovarian cancer still remains illustrated. Here, we sought to elucidate the regulatory function of CT on cell glucose metabolism in ovarian cancer. The treatment of CT on ovarian cancer cells effectively inhibited glucose uptake and lactate production in ovarian cancer cells. The expression levels of glycolysis-related proteins, such as GLUT1, LDHA, and HK2, were decreased by the treatment of CT detected by qRT-PCR and immunoblotting. Mechanistically, CT exerted its anti-tumor effect by targeting STAT3/SIRT3/HIF-1α signaling pathway in vitro and in vivo, which could be rescued by the introduction of SIRT3 shRNA in ovarian cancer cells. The clinical data showed that the expression level of STAT3 in ovarian cancer patients' sera and tissues was positively correlated with those of GLUT1, LDHA, HK2 and HIF-1α, but negatively with that of SIRT3These findings provide evidence that CT inhibited cellular glycolysis-induced cell growth and proliferation through repression of STAT3/SIRT3/HIF-1α signaling pathway, indicating that CT may be developed as a chemotherapeutic agent to treat ovarian cancer.
[Study on Variety Test of Salvia miltiorrhiza New Variety “Zhongdan 1”].[Pubmed: 30088870]
The new varieties of Salvia miltiorrhiza were bred by the variety comparison test.
