Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3553 - 3560 of 9359 hot products
| Catalog No. | Product Name |
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| BCC9018 | Memantine hydrochloride |
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An antagonist at the NMDA receptor, binding to the ion channel site. Used in the treatment of Parkinsonism.
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| BCC9047 | Miconazole nitrate |
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Antifungal agent. Inhibits lanosterol demethylase and induces formation of reactive oxygen species. Enhances the generation of mature oligodendrocytes from progenitor cells in vitro and promotes myelination in vivo. Attenuates disease severity in a mouse model of multiple sclerosis. Brain penetrant.
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| BCC9115 | Pemetrexed |
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High affinity dihydrofolate reductase inhibitor (Ki = 7 nM). Also inhibits thymidylate synthase, AICART and glycinamide ribonucleotide formyltransferase (Ki values are 109 nM, and 3.5 μM and 9.3 μM, respectively). Indirectly activates AMPK. Inhibits proliferation of cancer cell lines in vitro.
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| BCC9130 | Propofol |
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Intravenous general anesthetic and hypnotic with a mode of action which includes potentiation of GABA-mediated inhibitory synaptic transmission, direct activation of the GABAA receptor and inhibition of glutamate receptor mediated excitatory synaptic transmission. Also potentiates P2X4 receptor-mediated currents in P2X4-HEK293 cells.
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| BCC9143 | Senkyunolide G |
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1. Senkyunolide G and senkyunolide I could serve as pharmacokinetic markers for sepsis care.
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| BCC9194 | Zolpidem |
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Benzodiazepine agonist with high selectivity for α1-subunit-containing GABAA receptors (BZ/ω1 site) and very high intrinsic activity. Ki values are 20, 400 and ≥ 5000 nM for α1-, α2-/α3-, and α5-containing GABAA receptors respectively. Hypnotic that does not induce physical dependence.
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| BCC9195 | Zopiclone |
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A non benzodiazepine BZR agonist, with little difference in affinity for the BZ1 and BZ2 subtypes; however its CNS effects differ from those of other BZR ligands and this may be due to interaction with a different subunit.
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| BCC9214 | Aflatoxin G1 |
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Aflatoxin G1 (AFG1 ), a member of the AF family with cytotoxic and carcinogenic properties, could cause DNA damage in alveolar type II (AT-II) cells and induce lung adenocarcinoma. AFG1 induces TNF-α-dependent lung inflammation, which upregulates CYP2A13 to promote the metabolic activation of AFG1 and enhance oxidative DNA damage in AT-II cells. Dillapiol as a specific inhibitor of aflatoxin G1 production, it inhibited aflatoxin G1 production by Aspergillus parasiticus with an IC50 value of 0.15 microM.
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