Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC1974 | SU5416 |
| Inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET. Displays no activity against EGFR, HER2, IGF1R and PDGFR. Inhibits tumor vascularization and growth of multiple tumor types. | |
| BCC1975 | Tacalcitol |
| Synthetic vitamin D3 analog. Promotes normal bone development by regulating calcium. Modulates immunological and inflammatory processes; induces nerve growth factor production in epidermal keratinocytes. | |
| BCC1990 | Tedizolid |
| Torezolid (also known as TR-701 and now tedizolid) is an oxazolidinone antibiotic drug. | |
| BCC2000 | Tiotropium Bromide |
| Potent muscarinic receptor antagonist. Inhibits electrical field stimulation-induced contraction of guinea pig trachea in vitro (IC50 = 0.17 nM). Induces smooth muscle relaxation and bronchodilation. | |
| BCC2021 | UK-5099 |
| Inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC). | |
| BCC2027 | Valspodar |
| P-glycoprotein (P-gp) modulator; inhibits P-gp-mediated multidrug-resistance (MDR). Reverses resistance to several cytotoxic drugs including mitoxantrone and doxorubicin (resistance factors are 2.0 and 6.5 respectively) in human MDR cancer cell lines. Non-immunosuppressive analog of cyclosporin A. | |
| BCC2034 | VD2-D3 |
| VD2-D3 is a deuterated form of vitamin D. | |
| BCC2041 | Vilazodone Hydrochloride |
| Potent 5-HT1A partial agonist and serotonin-selective reuptake inhibitor (SSRI) (IC50 values are 0.2 and 0.5 nM respectively). Antidepressant. | |
