Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC6529 | GNF-7 |
| Ras signaling inhibitor; inhibits Ack1 and germinal center kinase (GCK). Suppresses proliferation, and induces cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations. Prolongs survival in a leukemia cell xenotransplantation model in mice. | |
| BCC6530 | 2-NBDG |
| Fluorescent glucose analog for visualizing glucose uptake into living cells. | |
| BCC6548 | DL-AP4 |
| Broad spectrum EAA ligand. Separate isomers D-AP4 and L-AP4 also available. | |
| BCC6549 | D-AP4 |
| Broad spectrum excitatory amino acid receptor antagonist. Also agonist at the quisqualate-sensitized AP6 site in hippocampus where it is less potent than L-AP4. DL Mixture and L-isomer also available. | |
| BCC6550 | L-AP4 |
| Selective group III metabotropic glutamate receptor agonist. Synaptic depressant. Agonist at the quisqualate-sensitized AP6 site in hippocampus. Also available as part of the Group III mGlu Receptor and Mixed mGlu Receptor. DL Mixture and D-isomer also available. | |
| BCC6551 | DL-AP7 |
| First generation phosphono NMDA antagonist. Anticonvulsant. | |
| BCC6552 | DL-AP5 |
| Potent NMDA antagonist. Separate isomers D-AP5, L-AP5 and sodium salt DL-AP5 Sodium salt also available. | |
| BCC6553 | D-AP5 |
| Widely used competitive NMDA antagonist. More active form of AP5. Also agonist at quisqualate-sensitized AP6 site where it is less potent than the L-isomer, L-AP5. Also available as part of the Mixed NMDA Receptor or as a mixed isomer DL-AP5. | |
