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(2-Aminoethyl)phosphonic acid

CAS# 2041-14-7

(2-Aminoethyl)phosphonic acid

Catalog No. BCN1762----Order now to get a substantial discount!

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Quality Control of (2-Aminoethyl)phosphonic acid

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Chemical structure

(2-Aminoethyl)phosphonic acid

3D structure

Chemical Properties of (2-Aminoethyl)phosphonic acid

Cas No. 2041-14-7 SDF Download SDF
PubChem ID 339 Appearance Powder
Formula C2H8NO3P M.Wt 125.06
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-aminoethylphosphonic acid
SMILES C(CP(=O)(O)O)N
Standard InChIKey QQVDJLLNRSOCEL-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of (2-Aminoethyl)phosphonic acid

The Tetrahymena pyriformis

Biological Activity of (2-Aminoethyl)phosphonic acid

Description1. 2-Aminoethylphosphonic acid as an indicator of Tetrahymena pyriformis W growth in protein-quality evaluation assay.

(2-Aminoethyl)phosphonic acid Dilution Calculator

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(2-Aminoethyl)phosphonic acid Molarity Calculator

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Preparing Stock Solutions of (2-Aminoethyl)phosphonic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 7.9962 mL 39.9808 mL 79.9616 mL 159.9232 mL 199.904 mL
5 mM 1.5992 mL 7.9962 mL 15.9923 mL 31.9846 mL 39.9808 mL
10 mM 0.7996 mL 3.9981 mL 7.9962 mL 15.9923 mL 19.9904 mL
50 mM 0.1599 mL 0.7996 mL 1.5992 mL 3.1985 mL 3.9981 mL
100 mM 0.08 mL 0.3998 mL 0.7996 mL 1.5992 mL 1.999 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on (2-Aminoethyl)phosphonic acid

A new amido phosphonate derivative of carboxymethylcellulose with an osteogenic activity and which is capable of interacting with any Ti surface.[Pubmed:20740601]

J Biomed Mater Res A. 2010 Oct;95(1):58-67.

A new phosphonate derivative of carboxymethylcellulose (CMC) was recently synthesized (CMCAPh). The phosphonate polysaccharide was obtained by using a carbodiimide-like activating agent for carboxylic groups and 2-aminoethyl-phosphonic acid to create an amide bond between the amine of the phosphonate agent and the carboxylic acids of CMC. The polymer was characterized by (31)P NMR, FT-IR, and potentiometric titration. CMCAPh showed different properties from CMC and its amidated derivative polymer CMCA. The behavior in solution of CMCAPh polymer towards normal human osteoblasts (NHOst) was studied in vitro, monitoring the cell proliferation, cell differentiation, and osteogenic activity and was then compared with the amidic derivative of carboxymethylcellulose (CMCA). Furthermore, CMCAPh was used to coat titania disks with the aim of increasing the osteogenic activity of implant surfaces. The polymer film on the titania surface was characterized by AFM and TOF-SIMS analysis. An ATR FT-IR study was carried out to evaluate the polymer bonding mode onto the titanium surface. Osteoblast morphology was evaluated by SEM. Adhesion analysis of NHOst demonstrated a better adhesion on the titanium surface coated with CMCAPh than on the bare titanium surface.

2-Aminoethylphosphonic acid as an indicator of Tetrahymena pyriformis W growth in protein-quality evaluation assay.[Pubmed:96851]

Br J Nutr. 1978 Jul;40(1):83-90.

1. The concentration of 2-aminoethylphosphonic acid (AEP) in 96 h cultures of Tetrahymena pyriformis W was studied in order to apply it as an indicator in the assay of the relative nutritive value (RNV; protozoa population with test protein:protozoa population with whole-egg powder) of protein. Foodstuffs and food mixtures of different protein contents and qualities were used as test samples. 2. RNV values based on AEP determination (RNVAEP) were compared with corresponding values calculated from protozoa counts (RNVpc), as well as with biological value (BV) and net protein utilization (NPU) of the same proteins assayed on rats. 3. Both for foodstuffs and food mixtures highly significant correlations were found between RNVAEP and RNVpc, RNVAEP and both BV and NPU, and RNVpc and both BV and NPU. 4. AEP content in the protozoal suspension was preferred to cell count as a measure of growth response, since it took into account large differences in cell dimensions that were observed between cultures grown with different test proteins.

Protein binding to amphoteric polymer brushes grafted onto a porous hollow-fiber membrane.[Pubmed:17918859]

Biotechnol Prog. 2007 Nov-Dec;23(6):1425-30.

Three kinds of ampholites, i.e., 3-aminopropionic acid (NH2C2H4COOH), (2-Aminoethyl)phosphonic acid (NH2C2H4PO3H2), and 2-aminoethane-1-sulfonic acid (NH2C2H4SO3H), were introduced into an epoxy group-containing polymer brush grafted onto a porous hollow-fiber membrane with a porosity of 70% and pore size of 0.36 microm. The amphoteric group density of the hollow-fiber ranged from 0.50 to 0.72 mmol/g. Three kinds of proteins, i.e., lactoferrin (Lf), cytochrome c (Cyt c), and lysozyme (Ly), were captured by the amphoteric polymer brush during the permeation of the protein solution across the ampholite-immobilized porous hollow-fiber membrane. Multilayer binding of the protein to the amphoteric polymer brush, with a degree of multilayer binding of 3.3, 8.6, and 15 for Lf, Cyt c, and Ly, respectively, with the (2-Aminoethyl)phosphonic acid-immobilized porous hollow-fiber membrane, was demonstrated with a negligible diffusional mass-transfer resistance of the protein to the ampholite immobilized. The 2-aminoethane-1-sulfonic acid-immobilized porous hollow-fiber membrane exhibited the lowest initial flux of the protein solution, 0.41 m/h at a transmembrane pressure of 0.1 MPa and 298 K, and the highest equilibrium binding capacity of the protein, e.g., 130 mg/g for lysozyme. Extension and shrinkage of the amphoteric polymer brushes were observed during the binding and elution of the proteins.

Description

(2-Aminoethyl)phosphonic acid is an endogenous metabolite.

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