1(10)-Aristolen-2-oneCAS# 28398-06-3 |
Quality Control & MSDS
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| Cas No. | 28398-06-3 | SDF | Download SDF |
| PubChem ID | 71717616 | Appearance | Oil |
| Formula | C15H22O | M.Wt | 218.33 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1aR,7R,7aR,7bS)-1,1,7,7a-tetramethyl-1a,2,3,6,7,7b-hexahydrocyclopropa[a]naphthalen-5-one | ||
| SMILES | CC1CC(=O)C=C2C1(C3C(C3(C)C)CC2)C | ||
| Standard InChIKey | OHIBAYUTHVYXER-JWFUOXDNSA-N | ||
| Standard InChI | InChI=1S/C15H22O/c1-9-7-11(16)8-10-5-6-12-13(14(12,2)3)15(9,10)4/h8-9,12-13H,5-7H2,1-4H3/t9-,12-,13+,15+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Elionurus Muticus (Spreng) Kunth.
| Description | 1. 1(10)-Aristolen-2-one has antifungal activity. |
| Targets | Antifection |
1(10)-Aristolen-2-one Dilution Calculator
1(10)-Aristolen-2-one Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.5802 mL | 22.9011 mL | 45.8022 mL | 91.6045 mL | 114.5056 mL |
| 5 mM | 0.916 mL | 4.5802 mL | 9.1604 mL | 18.3209 mL | 22.9011 mL |
| 10 mM | 0.458 mL | 2.2901 mL | 4.5802 mL | 9.1604 mL | 11.4506 mL |
| 50 mM | 0.0916 mL | 0.458 mL | 0.916 mL | 1.8321 mL | 2.2901 mL |
| 100 mM | 0.0458 mL | 0.229 mL | 0.458 mL | 0.916 mL | 1.1451 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antifungal Activity of the Essential Oil of Elionurus Muticus (Spreng) Kunth from Zimbabwe against Candida albicans, C. krusei and Cryptococcus neoformans
Journal of Multidisciplinary Engineering Science and Technology (JMEST), 2016, 3(7):5331-5.
Cultivated Elionurus muticus (Spreng.) Kunth (Gramineae) plant parts were steam distilled for essential oil and evaluated in-vitro for antifungal activity against Candida albicans, C. krusei and Cryptococcus neoformans using agar broth dilution and disc diffusion methods and the activity compared with commercial citral and Cymbopogon citratus DC (Stapf) (lemongrass) oils by measuring the growth inhibition diameter. E. muticus oils showed fungicidal activity with MIC and MFC values between 0.5-10μg/mL. E. muticus whole plant oil showed greater antifungal activity against C. albicans than citral and lemongrass oils. E. muticus whole plant essential oil contains citral and ∆ 1(10)-Aristolen-2-one as major components, both are known antifungal compounds. Their unique presence in one plant extract could have significant impact in treating mycotic diseases and other opportunistic infections and for use in clinical aromatherapy and in complementary and alternative medicines.
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