1,5,15-Tri-O-methylmorindolCAS# 942609-65-6 |
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3D structure
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| Cas No. | 942609-65-6 | SDF | Download SDF |
| PubChem ID | 16203753 | Appearance | Yellow powder |
| Formula | C18H16O6 | M.Wt | 328.3 |
| Type of Compound | Anthraquinones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-hydroxy-1,5-dimethoxy-6-(methoxymethyl)anthracene-9,10-dione | ||
| SMILES | COCC1=C(C2=C(C=C1)C(=O)C3=C(C2=O)C=CC(=C3OC)O)OC | ||
| Standard InChIKey | HEVJQUHAJKODII-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Morinda citrifolia
| Description | 1. 1,5,15-Tri-O-methylmorindol has effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA. |
1,5,15-Tri-O-methylmorindol Dilution Calculator
1,5,15-Tri-O-methylmorindol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.046 mL | 15.23 mL | 30.4599 mL | 60.9199 mL | 76.1499 mL |
| 5 mM | 0.6092 mL | 3.046 mL | 6.092 mL | 12.184 mL | 15.23 mL |
| 10 mM | 0.3046 mL | 1.523 mL | 3.046 mL | 6.092 mL | 7.615 mL |
| 50 mM | 0.0609 mL | 0.3046 mL | 0.6092 mL | 1.2184 mL | 1.523 mL |
| 100 mM | 0.0305 mL | 0.1523 mL | 0.3046 mL | 0.6092 mL | 0.7615 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni).[Pubmed:17480098]
J Nat Prod. 2007 May;70(5):754-7.
A new anthraquinone, 1,5,15-Tri-O-methylmorindol (1), and two new saccharide fatty acid esters, 2-O-(beta-D-glucopyranosyl)-1-O-hexanoyl-beta-D-gluropyranose (4) and 2-O-(beta-D-glucopyranosyl)-1-O-octanoyl-beta-D-gluropyranose (5), have been isolated from a methanol extract of the fruits of Morinda citrifolia (noni) along with 10 known compounds, namely, two anthraquinones (2, 3), six saccharide fatty acid esters (6-11), an iridoid glycoside (12), and a flavanol glycoside (13). Upon evaluation of six compounds (5-7, 9, 10, and 13) for inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation (1 microg/ear) in mice, four saccharide fatty acid esters, 5-7 and 9, exhibited potent anti-inflammatory activity, with ID50 values of 0.46-0.79 mg per ear. In addition, when compounds 1-13 were evaluated against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA, all of the compounds exhibited moderate inhibitory effects (IC50 values of 386-578 mol ratio/32 pmol TPA).
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