1-HydroxyrutaecarpineCAS# 53600-24-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 53600-24-1 | SDF | Download SDF |
PubChem ID | 10447696 | Appearance | Yellow powder |
Formula | C18H13N3O2 | M.Wt | 303.3 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
SMILES | C1CN2C(=NC3=C(C2=O)C=CC=C3O)C4=C1C5=CC=CC=C5N4 | ||
Standard InChIKey | IBBYAIMGJMOBLQ-UHFFFAOYSA-N | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | 1. 1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro. 2. 1-Hydroxyrutaecarpine exhibits antiplatelet activity induced by AA and shows an IC50 value of ca.1-2 micrograms/ml. 3. 1-Hydroxyrutaecarpine displays moderate inhibitory activity on those enzymes(Cathepsins B, L and K) at the concentration of 125 ug/ml. |
1-Hydroxyrutaecarpine Dilution Calculator
1-Hydroxyrutaecarpine Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.2971 mL | 16.4853 mL | 32.9707 mL | 65.9413 mL | 82.4266 mL |
5 mM | 0.6594 mL | 3.2971 mL | 6.5941 mL | 13.1883 mL | 16.4853 mL |
10 mM | 0.3297 mL | 1.6485 mL | 3.2971 mL | 6.5941 mL | 8.2427 mL |
50 mM | 0.0659 mL | 0.3297 mL | 0.6594 mL | 1.3188 mL | 1.6485 mL |
100 mM | 0.033 mL | 0.1649 mL | 0.3297 mL | 0.6594 mL | 0.8243 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Perillyl alcohol
Catalog No.:BCN3876
CAS No.:536-59-4
- Ethionamide
Catalog No.:BCC3778
CAS No.:536-33-4
- 5'-Iodoresiniferatoxin
Catalog No.:BCC7031
CAS No.:535974-91-5
- Secolongifolenediol
Catalog No.:BCN6989
CAS No.:53587-37-4
- H-Tyr-OBzl.TosOH
Catalog No.:BCC3124
CAS No.:53587-11-4
- 5-Galloylquinic acid
Catalog No.:BCN3060
CAS No.:53584-43-3
- Beta-Amyrenonol acetate
Catalog No.:BCN4620
CAS No.:5356-56-9
- (-)-Bicuculline methochloride
Catalog No.:BCN3763
CAS No.:53552-05-9
- Diaveridine
Catalog No.:BCC8936
CAS No.:5355-16-8
- Benzoyl-L-histidine
Catalog No.:BCC8866
CAS No.:5354-94-9
- Apigenin 7-O-methylglucuronide
Catalog No.:BCN5708
CAS No.:53538-13-9
- Luteolin-3-O-beta-D-glucuronide
Catalog No.:BCN3826
CAS No.:53527-42-7
- GMQ hydrochloride
Catalog No.:BCC6351
CAS No.:5361-15-9
- Teucvin
Catalog No.:BCN8375
CAS No.:53625-15-3
- Vindesine
Catalog No.:BCN2607
CAS No.:53643-48-4
- Dehydrobruceantin
Catalog No.:BCN7617
CAS No.:53662-98-9
- 4,6-Dimethoxy-2H-1-benzopyran-2-one
Catalog No.:BCN3452
CAS No.:53666-78-7
- O-1918
Catalog No.:BCC7313
CAS No.:536697-79-7
- ICI 89406
Catalog No.:BCC6807
CAS No.:53671-71-9
- QX 222
Catalog No.:BCC6906
CAS No.:5369-00-6
- QX 314 chloride
Catalog No.:BCC7326
CAS No.:5369-03-9
- 3-Acetyl-5-Hydroxymethyl-7-Hydroxycoumarin
Catalog No.:BCC9201
CAS No.:53696-74-5
- Diperodon HCl
Catalog No.:BCC3766
CAS No.:537-12-2
- Tropacocaine
Catalog No.:BCN1934
CAS No.:537-26-8
Indolopyridoquinazoline alkaloids with antiplatelet aggregation activity from Zanthoxylum integrifoliolum.[Pubmed:8657756]
Planta Med. 1996 Apr;62(2):175-6.
Bioassay-guided fractionation led to the isolation of three indolopyridoquinazoline alkaloids, 1-Hydroxyrutaecarpine, rutaecarpine, and 1-methoxyrutaecarpine as the active principles of antiplatelet aggregation in vitro, from the chloroform-soluble part of the fruit of Zanthoxylum integrifoliolum (Rutaceae). 1-Hydroxyrutaecarpine exhibited antiplatelet activity induced by AA and showed an IC50 value of ca. 1-2 micrograms/ml.
New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum.[Pubmed:15931588]
Planta Med. 2005 May;71(5):470-5.
Three new alkaloids, 7,8-dehydro-1-methoxyrutaecarpine, isodecarine, and 8-demethyloxychelerythrine, together with sixteen known compounds, norchelerythrine, oxychelerythrine, decarine, dihydrocherythrinylacetaldehyde, 6-acetonyldihydrochelerythrine, rutaecarpine, 1-Hydroxyrutaecarpine, gamma-fagarine, skimmianine, (-)-matairesinol, (-)-isoarctigenin, (+)-epipinoresinol, d-sesamin, lupeol, canthin-6-one, and arnottianamide have been isolated from the root bark of Zanthoxylum integrifoliolum. The structures of these new compounds were determined through spectral analyses. Among the isolates, 7,8-dehydro-1-methoxyrutaecarpine, norchelerythrine, oxychelerythrine, dihydrocherythrinylacetaldehyde, 6-acetonyldihydrochelerythrine, 1-Hydroxyrutaecarpine, gamma-fagarine, skimmianine, (-)-matairesinol, and canthin-6-one exhibited cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro.