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1-Methoxymethyl-beta-carboline

CAS# 55854-60-9

1-Methoxymethyl-beta-carboline

2D Structure

Catalog No. BCN7911----Order now to get a substantial discount!

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Quality Control of 1-Methoxymethyl-beta-carboline

3D structure

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1-Methoxymethyl-beta-carboline

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Chemical Properties of 1-Methoxymethyl-beta-carboline

Cas No. 55854-60-9 SDF Download SDF
PubChem ID 5382686 Appearance Powder
Formula C13H12N2O M.Wt 212.25
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-(methoxymethyl)-9H-pyrido[3,4-b]indole
SMILES COCC1=NC=CC2=C1NC3=CC=CC=C23
Standard InChIKey OELXEULZDKMFCS-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H12N2O/c1-16-8-12-13-10(6-7-14-12)9-4-2-3-5-11(9)15-13/h2-7,15H,8H2,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 1-Methoxymethyl-beta-carboline

The herbs of Picrasma javanica

Biological Activity of 1-Methoxymethyl-beta-carboline

Description1-Methoxymethyl-beta-carboline is a natural product from Picrasma javanica.

Protocol of 1-Methoxymethyl-beta-carboline

Structure Identification
Biol Pharm Bull. 1993 Feb;16(2):103-6.

Fluorometric determination of L-tryptophan with methoxyacetaldehyde.[Pubmed: 8364442]


METHODS AND RESULTS:
It was observed in our laboratory that methoxyacetaldehyde induced strong fluorescence with L-tryptophan in the presence of NaNO2 at pH 2.75. The reaction mixture was heated at 80 degrees C for 15 min and the fluorescence was measured at the excitation wavelength, 253 nm and the emission, 450 nm. Amino acids other than L-tryptophan did not produce fluorescence under the conditions employed. A good linear working curve was observed between 25 pmol/50 microliters and 500 pmol/50 microliters of L-tryptophan. The limit of determination for L-tryptophan was 10 pmol/50 microliters. The coefficient of variation of the measurements (n = 5) was 1.5% for 250 pmol/50 microliters of L-tryptophan. The proposed method was successfully applied to the analyses of tryptophan in a pooled human serum. Total tryptophan was determined after deproteinization with trichloroacetic acid, and free tryptophan was determined using the ultrafiltrate of a pooled human serum. Analytical recoveries of total and free tryptophan were 98.8% and 99.1%, respectively.
CONCLUSIONS:
The fluorescent products of L-tryptophan and methoxyacetaldehyde were characterized as beta-carboline and 1-Methoxymethyl-beta-carboline by the use of liquid chromatography-mass spectrometry (LC-MS) and HPLC.

1-Methoxymethyl-beta-carboline Dilution Calculator

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1-Methoxymethyl-beta-carboline Molarity Calculator

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Preparing Stock Solutions of 1-Methoxymethyl-beta-carboline

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7114 mL 23.5571 mL 47.1143 mL 94.2285 mL 117.7856 mL
5 mM 0.9423 mL 4.7114 mL 9.4229 mL 18.8457 mL 23.5571 mL
10 mM 0.4711 mL 2.3557 mL 4.7114 mL 9.4229 mL 11.7786 mL
50 mM 0.0942 mL 0.4711 mL 0.9423 mL 1.8846 mL 2.3557 mL
100 mM 0.0471 mL 0.2356 mL 0.4711 mL 0.9423 mL 1.1779 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 1-Methoxymethyl-beta-carboline

Fluorometric determination of L-tryptophan with methoxyacetaldehyde.[Pubmed:8364442]

Biol Pharm Bull. 1993 Feb;16(2):103-6.

It was observed in our laboratory that methoxyacetaldehyde induced strong fluorescence with L-tryptophan in the presence of NaNO2 at pH 2.75. The reaction mixture was heated at 80 degrees C for 15 min and the fluorescence was measured at the excitation wavelength, 253 nm and the emission, 450 nm. Amino acids other than L-tryptophan did not produce fluorescence under the conditions employed. A good linear working curve was observed between 25 pmol/50 microliters and 500 pmol/50 microliters of L-tryptophan. The limit of determination for L-tryptophan was 10 pmol/50 microliters. The coefficient of variation of the measurements (n = 5) was 1.5% for 250 pmol/50 microliters of L-tryptophan. The proposed method was successfully applied to the analyses of tryptophan in a pooled human serum. Total tryptophan was determined after deproteinization with trichloroacetic acid, and free tryptophan was determined using the ultrafiltrate of a pooled human serum. Analytical recoveries of total and free tryptophan were 98.8% and 99.1%, respectively. The fluorescent products of L-tryptophan and methoxyacetaldehyde were characterized as beta-carboline and 1-Methoxymethyl-beta-carboline by the use of liquid chromatography-mass spectrometry (LC-MS) and HPLC.

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