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Pennogenin 3-O-beta-chacotrioside

CAS# 55916-52-4

Pennogenin 3-O-beta-chacotrioside

Catalog No. BCN6707----Order now to get a substantial discount!

Product Name & Size Price Stock
Pennogenin 3-O-beta-chacotrioside: 5mg $104 In Stock
Pennogenin 3-O-beta-chacotrioside: 10mg Please Inquire In Stock
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Quality Control of Pennogenin 3-O-beta-chacotrioside

Number of papers citing our products

Chemical structure

Pennogenin 3-O-beta-chacotrioside

3D structure

Chemical Properties of Pennogenin 3-O-beta-chacotrioside

Cas No. 55916-52-4 SDF Download SDF
PubChem ID 21626520 Appearance Powder
Formula C45H72O17 M.Wt 885.1
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1R,2S,4S,5'R,6R,7S,8S,9S,12S,13R,16S)-8-hydroxy-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
SMILES CC1CCC2(C(C3(C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)O)C)OC1
Standard InChIKey NABPSKKFOWENEB-KUYDPMQHSA-N
Standard InChI InChI=1S/C45H72O17/c1-19-9-14-44(55-18-19)22(4)45(54)29(62-44)16-27-25-8-7-23-15-24(10-12-42(23,5)26(25)11-13-43(27,45)6)58-41-38(61-40-35(52)33(50)31(48)21(3)57-40)36(53)37(28(17-46)59-41)60-39-34(51)32(49)30(47)20(2)56-39/h7,19-22,24-41,46-54H,8-18H2,1-6H3/t19-,20+,21+,22-,24+,25-,26+,27+,28-,29+,30+,31+,32-,33-,34-,35-,36+,37-,38-,39+,40+,41-,42+,43+,44-,45-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pennogenin 3-O-beta-chacotrioside

The rhizomes of Paris yunnanensis Franch.

Protocol of Pennogenin 3-O-beta-chacotrioside

Structure Identification
Chemical & pharmaceutical bulletin, 1989, 37(1),116-8.

Studies on the Constituents of Heloniopsis orientalis (THUNB.) C. TANAKA.[Reference: WebLink]


METHODS AND RESULTS:
The constituents of the fresh whole plants of Heloniopsis orientalis (THUNB.) C. TANAKA (Liliaceae) were investigated and five steroidal components were obtained.
CONCLUSIONS:
Their chemical structures were characterized as dioscin (1), Pennogenin 3-O-beta-chacotrioside(T-c)(2), pregnadienolone 3-O-beta-chacotrioside(P-d)(3), 26-O-β-D-glucopyranosyl17-dehydrokryptoenin 3-O-β-chacotrioside (4) and 12-O-β-D-galactopyranosyl helonigenin 3-O-β-D-allomethylopyranosyl-(1→5)-β-D-apiofuranoside (5).

Pennogenin 3-O-beta-chacotrioside Dilution Calculator

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Pennogenin 3-O-beta-chacotrioside Molarity Calculator

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Preparing Stock Solutions of Pennogenin 3-O-beta-chacotrioside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1298 mL 5.6491 mL 11.2982 mL 22.5963 mL 28.2454 mL
5 mM 0.226 mL 1.1298 mL 2.2596 mL 4.5193 mL 5.6491 mL
10 mM 0.113 mL 0.5649 mL 1.1298 mL 2.2596 mL 2.8245 mL
50 mM 0.0226 mL 0.113 mL 0.226 mL 0.4519 mL 0.5649 mL
100 mM 0.0113 mL 0.0565 mL 0.113 mL 0.226 mL 0.2825 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1. Anti-colorectal cancer activity.

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