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Zingiberen newsaponin

CAS# 91653-50-8

Zingiberen newsaponin

Catalog No. BCN2942----Order now to get a substantial discount!

Product Name & Size Price Stock
Zingiberen newsaponin: 5mg $161 In Stock
Zingiberen newsaponin: 10mg Please Inquire In Stock
Zingiberen newsaponin: 20mg Please Inquire Please Inquire
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Quality Control of Zingiberen newsaponin

Number of papers citing our products

Chemical structure

Zingiberen newsaponin

3D structure

Chemical Properties of Zingiberen newsaponin

Cas No. 91653-50-8 SDF Download SDF
PubChem ID 102475150 Appearance Powder
Formula C51H82O22 M.Wt 1047.2
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)-2-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
SMILES CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)O)OC9C(C(C(C(O9)CO)O)O)O)O)O)OC2C(C(C(C(O2)C)O)O)O)C)C)C)OC1
Standard InChIKey XJOTXMLDNWCDRH-HAUZKCKMSA-N
Standard InChI InChI=1S/C51H82O22/c1-20-8-13-51(64-19-20)21(2)32-28(73-51)15-27-25-7-6-23-14-24(9-11-49(23,4)26(25)10-12-50(27,32)5)66-48-44(72-45-38(60)36(58)33(55)22(3)65-45)40(62)42(31(18-54)69-48)70-47-41(63)43(35(57)30(17-53)68-47)71-46-39(61)37(59)34(56)29(16-52)67-46/h6,20-22,24-48,52-63H,7-19H2,1-5H3/t20-,21+,22+,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34-,35-,36-,37+,38-,39-,40+,41-,42-,43+,44-,45+,46+,47+,48-,49+,50+,51-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Zingiberen newsaponin

The rhizomes of Paris yunnanensis Franch.

Biological Activity of Zingiberen newsaponin

Description1. Zingiberensis newsaponin I exhibits induction effect on platelet aggregation. 2. Zingiberensis saponin can inhibit the proliferation of a panel of established human and murine cancer cell lines in vitro, its proliferation inhibitory effect is associated with its apoptosis-inducing effect by activation of caspase-3 and caspase-9 and specific proteolytic cleavage of poly (ADP-ribose) polymerase, thus, zingiberensis saponin is an effective natural agent for cancer therapy.
TargetsPAFR | Caspase | PARP

Zingiberen newsaponin Dilution Calculator

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Zingiberen newsaponin Molarity Calculator

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Preparing Stock Solutions of Zingiberen newsaponin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.9549 mL 4.7746 mL 9.5493 mL 19.0985 mL 23.8732 mL
5 mM 0.191 mL 0.9549 mL 1.9099 mL 3.8197 mL 4.7746 mL
10 mM 0.0955 mL 0.4775 mL 0.9549 mL 1.9099 mL 2.3873 mL
50 mM 0.0191 mL 0.0955 mL 0.191 mL 0.382 mL 0.4775 mL
100 mM 0.0095 mL 0.0477 mL 0.0955 mL 0.191 mL 0.2387 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Zingiberen newsaponin

[Study on steroidal saponins from Dioscorea zingiberensis and their platelet aggregation activities].[Pubmed:25612440]

Zhongguo Zhong Yao Za Zhi. 2014 Oct;39(19):3782-7.

Using the absorbent resin, silica gel and ODS column chromatography as well as semi-preparative HPLC, ten compounds were isolated from 70% ethanol extract of tubers of Dioscorea zingiberensis C. H. Wright, and their structures were elucidated as trigoneoside XIIIa (1), parvifloside (2), trigoneoside IVa (3), deltoside (4), protobioside (5), lilioglycoside k (6), zingiberensis newsaponin I (7), deltonin (8), prosapogenin A of dioscin (9), and trillin (10) on the basis of NMR and MS spectral data analysis. Among these compounds, 1, 3, 5 and 6 were isolated from this plant for the first time. In the screening test on platelet aggregation, compounds 7 and 8 exhibited induction effect on platelet aggregation, while compound 9 exhibited significant inhibitory effect on platelet aggregation in vitro.

Description

Zingiberen Newsaponin is extracted from isolated from Dioscorea zingiberensis.

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