Columbianetin beta-D-glucopyranosideCAS# 55836-35-6 |
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| Cas No. | 55836-35-6 | SDF | Download SDF |
| PubChem ID | 6453269 | Appearance | Powder |
| Formula | C20H24O9 | M.Wt | 408.4 |
| Type of Compound | Coumarins | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (8S)-8-[2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-8,9-dihydrofuro[2,3-h]chromen-2-one | ||
| SMILES | CC(C)(C1CC2=C(O1)C=CC3=C2OC(=O)C=C3)OC4C(C(C(C(O4)CO)O)O)O | ||
| Standard InChIKey | UCJHITBUIWHISE-GGECFJTPSA-N | ||
| Standard InChI | InChI=1S/C20H24O9/c1-20(2,29-19-17(25)16(24)15(23)12(8-21)27-19)13-7-10-11(26-13)5-3-9-4-6-14(22)28-18(9)10/h3-6,12-13,15-17,19,21,23-25H,7-8H2,1-2H3/t12-,13+,15-,16+,17-,19+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The root of Angelica gigas
| Description | 1. Columbianetin-beta-D-glucopyranoside shows strong inhibiting activity against platelet aggregation. 2. Columbianetin-beta-D-glucopyranoside exhibits anti-inflammatory and analgesic properties. |
| Targets | Immunology & Inflammation related |
Columbianetin beta-D-glucopyranoside Dilution Calculator
Columbianetin beta-D-glucopyranoside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4486 mL | 12.2429 mL | 24.4858 mL | 48.9716 mL | 61.2145 mL |
| 5 mM | 0.4897 mL | 2.4486 mL | 4.8972 mL | 9.7943 mL | 12.2429 mL |
| 10 mM | 0.2449 mL | 1.2243 mL | 2.4486 mL | 4.8972 mL | 6.1214 mL |
| 50 mM | 0.049 mL | 0.2449 mL | 0.4897 mL | 0.9794 mL | 1.2243 mL |
| 100 mM | 0.0245 mL | 0.1224 mL | 0.2449 mL | 0.4897 mL | 0.6121 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Studies of the active constituents of the Chinese drug "duhuo" Angelica pubescents].[Pubmed:2618698]
Yao Xue Xue Bao. 1989;24(7):546-51.
Eight coumarins isolated from the alcohol extract of the Chinese drug "Duhuo", the root of Angelica pubescents Maxim. f. biserrata Shan et Yuan (Umbelliferae) were elucidated to be columbianetin (I), columbianetin acetate (II), columbiadin (III), osthol (IV), isoimperatorin (V), bergapten (VI), xanthotoxin (VII), and columbianetin-beta-D-glucopyranoside (VIII), by chemical and spectral analysis, compound VIII was isolated from plant for the first time. All these coumarins were tested on platelet aggregation induced by 2 microns ADP. I, II, III, IV and VIII showed strong inhibiting activity against platelet aggregation.
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