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Columbianetin beta-D-glucopyranoside

CAS# 55836-35-6

Columbianetin beta-D-glucopyranoside

Catalog No. BCN8222----Order now to get a substantial discount!

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Columbianetin beta-D-glucopyranoside: 5mg $334 In Stock
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Quality Control of Columbianetin beta-D-glucopyranoside

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Chemical structure

Columbianetin beta-D-glucopyranoside

3D structure

Chemical Properties of Columbianetin beta-D-glucopyranoside

Cas No. 55836-35-6 SDF Download SDF
PubChem ID 6453269 Appearance Powder
Formula C20H24O9 M.Wt 408.4
Type of Compound Coumarins Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (8S)-8-[2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-8,9-dihydrofuro[2,3-h]chromen-2-one
SMILES CC(C)(C1CC2=C(O1)C=CC3=C2OC(=O)C=C3)OC4C(C(C(C(O4)CO)O)O)O
Standard InChIKey UCJHITBUIWHISE-GGECFJTPSA-N
Standard InChI InChI=1S/C20H24O9/c1-20(2,29-19-17(25)16(24)15(23)12(8-21)27-19)13-7-10-11(26-13)5-3-9-4-6-14(22)28-18(9)10/h3-6,12-13,15-17,19,21,23-25H,7-8H2,1-2H3/t12-,13+,15-,16+,17-,19+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Columbianetin beta-D-glucopyranoside

The root of Angelica gigas

Biological Activity of Columbianetin beta-D-glucopyranoside

Description1. Columbianetin-beta-D-glucopyranoside shows strong inhibiting activity against platelet aggregation. 2. Columbianetin-beta-D-glucopyranoside exhibits anti-inflammatory and analgesic properties.
TargetsImmunology & Inflammation related

Columbianetin beta-D-glucopyranoside Dilution Calculator

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Columbianetin beta-D-glucopyranoside Molarity Calculator

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Preparing Stock Solutions of Columbianetin beta-D-glucopyranoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4486 mL 12.2429 mL 24.4858 mL 48.9716 mL 61.2145 mL
5 mM 0.4897 mL 2.4486 mL 4.8972 mL 9.7943 mL 12.2429 mL
10 mM 0.2449 mL 1.2243 mL 2.4486 mL 4.8972 mL 6.1214 mL
50 mM 0.049 mL 0.2449 mL 0.4897 mL 0.9794 mL 1.2243 mL
100 mM 0.0245 mL 0.1224 mL 0.2449 mL 0.4897 mL 0.6121 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Columbianetin beta-D-glucopyranoside

[Studies of the active constituents of the Chinese drug "duhuo" Angelica pubescents].[Pubmed:2618698]

Yao Xue Xue Bao. 1989;24(7):546-51.

Eight coumarins isolated from the alcohol extract of the Chinese drug "Duhuo", the root of Angelica pubescents Maxim. f. biserrata Shan et Yuan (Umbelliferae) were elucidated to be columbianetin (I), columbianetin acetate (II), columbiadin (III), osthol (IV), isoimperatorin (V), bergapten (VI), xanthotoxin (VII), and columbianetin-beta-D-glucopyranoside (VIII), by chemical and spectral analysis, compound VIII was isolated from plant for the first time. All these coumarins were tested on platelet aggregation induced by 2 microns ADP. I, II, III, IV and VIII showed strong inhibiting activity against platelet aggregation.

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