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1-Methyl-2-nonylquinolin-4(1H)-one

CAS# 68353-24-2

1-Methyl-2-nonylquinolin-4(1H)-one

Catalog No. BCN6585----Order now to get a substantial discount!

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1-Methyl-2-nonylquinolin-4(1H)-one: 5mg $213 In Stock
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Quality Control of 1-Methyl-2-nonylquinolin-4(1H)-one

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Chemical structure

1-Methyl-2-nonylquinolin-4(1H)-one

3D structure

Chemical Properties of 1-Methyl-2-nonylquinolin-4(1H)-one

Cas No. 68353-24-2 SDF Download SDF
PubChem ID 13967189 Appearance Powder
Formula C19H27NO M.Wt 285.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-methyl-2-nonylquinolin-4-one
SMILES CCCCCCCCCC1=CC(=O)C2=CC=CC=C2N1C
Standard InChIKey XIGBBPQAXHSVSN-UHFFFAOYSA-N
Standard InChI InChI=1S/C19H27NO/c1-3-4-5-6-7-8-9-12-16-15-19(21)17-13-10-11-14-18(17)20(16)2/h10-11,13-15H,3-9,12H2,1-2H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 1-Methyl-2-nonylquinolin-4(1H)-one

The fruits of Evodia rutaecarpa (Juss.) Benth.

Biological Activity of 1-Methyl-2-nonylquinolin-4(1H)-one

Description1. 1-Methyl-2-nonylquinolin-4(1H)-one has anti-inflammatory activity, it exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 microM.

1-Methyl-2-nonylquinolin-4(1H)-one Dilution Calculator

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1-Methyl-2-nonylquinolin-4(1H)-one Molarity Calculator

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Preparing Stock Solutions of 1-Methyl-2-nonylquinolin-4(1H)-one

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.5039 mL 17.5193 mL 35.0385 mL 70.0771 mL 87.5964 mL
5 mM 0.7008 mL 3.5039 mL 7.0077 mL 14.0154 mL 17.5193 mL
10 mM 0.3504 mL 1.7519 mL 3.5039 mL 7.0077 mL 8.7596 mL
50 mM 0.0701 mL 0.3504 mL 0.7008 mL 1.4015 mL 1.7519 mL
100 mM 0.035 mL 0.1752 mL 0.3504 mL 0.7008 mL 0.876 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 1-Methyl-2-nonylquinolin-4(1H)-one

Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa.[Pubmed:15490316]

Planta Med. 2004 Oct;70(10):904-8.

The n-hexane extract of the fruits of Evodia rutaecarpa showed a considerable inhibiting effect on leukotriene biosynthesis in human granulocytes. Bioassay-guided fractionation of the extract led to the isolation of the 5 quinolone alkaloids: 1-methyl-2-nonyl-4(1H)-quinolinone, 1-methyl-2-(6Z)-6-undecenyl-4(1H)-quinolinone, 1-methyl-2-(4Z,7Z)-4,7-tridecadienyl-4(1H)-quinolinone, evocarpine and 1-methyl-2-(6Z,9Z)-6,9-pentadecadienyl-4(1H)-quinolinone. The compounds exhibited inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1, 10.0, 10.1, 14,6 and 12.3 microM, respectively. Structure elucidation of the compounds was achieved by 1D and 2D NMR experiments and comparison of spectral data with literature data.

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