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2-Hydroxy-3-(hydroxymethyl)anthraquinone

CAS# 68243-30-1

2-Hydroxy-3-(hydroxymethyl)anthraquinone

Catalog No. BCN1380----Order now to get a substantial discount!

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Quality Control of 2-Hydroxy-3-(hydroxymethyl)anthraquinone

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Chemical structure

2-Hydroxy-3-(hydroxymethyl)anthraquinone

3D structure

Chemical Properties of 2-Hydroxy-3-(hydroxymethyl)anthraquinone

Cas No. 68243-30-1 SDF Download SDF
PubChem ID 44445519 Appearance Yellow cryst.
Formula C15H10O4 M.Wt 254.2
Type of Compound Anthraquinones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-hydroxy-3-(hydroxymethyl)anthracene-9,10-dione
SMILES C1=CC=C2C(=C1)C(=O)C3=CC(=C(C=C3C2=O)O)CO
Standard InChIKey LMXDYBJTJGPZPD-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of 2-Hydroxy-3-(hydroxymethyl)anthraquinone

Description1. 2-Hydroxy-3-(hydroxymethyl)anthraquinone exhibits quinone reductase (QR)- inducing activity in Hepa lclc7 cells, with the concentration required to double QR activity of 0.94 microM.

2-Hydroxy-3-(hydroxymethyl)anthraquinone Dilution Calculator

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2-Hydroxy-3-(hydroxymethyl)anthraquinone Molarity Calculator

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Preparing Stock Solutions of 2-Hydroxy-3-(hydroxymethyl)anthraquinone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.9339 mL 19.6696 mL 39.3391 mL 78.6782 mL 98.3478 mL
5 mM 0.7868 mL 3.9339 mL 7.8678 mL 15.7356 mL 19.6696 mL
10 mM 0.3934 mL 1.967 mL 3.9339 mL 7.8678 mL 9.8348 mL
50 mM 0.0787 mL 0.3934 mL 0.7868 mL 1.5736 mL 1.967 mL
100 mM 0.0393 mL 0.1967 mL 0.3934 mL 0.7868 mL 0.9835 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 2-Hydroxy-3-(hydroxymethyl)anthraquinone

Anthraquinones with quinone reductase-inducing activity and benzophenones from Morinda citrifolia (noni) roots.[Pubmed:18076142]

J Nat Prod. 2007 Dec;70(12):2049-52.

Two new benzophenones, morintrifolins A ( 1) and B ( 2), together with 14 known anthraquinones and four other known compounds, were isolated from a chloroform-soluble extract of Morinda citrifolia roots. Of the isolated compounds, four known anthraquinones, namely, 1,2-dihydroxyanthraquinone ( 3), 1,3-dihydroxy-2-methylanthraquinone ( 4), 2-Hydroxy-3-(hydroxymethyl)anthraquinone ( 5), and 1,3,6-trihydroxy-2-methylanthraquinone ( 6), exhibited quinone reductase (QR)- inducing activity in Hepa lclc7 cells, with concentrations required to double QR activity of 12.0, 8.1, 0.94, and 0.56 microM, respectively.

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