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14-Deoxy-17-hydroxyandrographolide

CAS# 869384-82-7

14-Deoxy-17-hydroxyandrographolide

2D Structure

Catalog No. BCN4560----Order now to get a substantial discount!

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14-Deoxy-17-hydroxyandrographolide: 5mg $989 In Stock
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Quality Control of 14-Deoxy-17-hydroxyandrographolide

3D structure

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14-Deoxy-17-hydroxyandrographolide

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Chemical Properties of 14-Deoxy-17-hydroxyandrographolide

Cas No. 869384-82-7 SDF Download SDF
PubChem ID 11631693 Appearance Powder
Formula C20H32O5 M.Wt 352.47
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[2-[(1R,2S,4aS,5R,6R,8aS)-6-hydroxy-2,5-bis(hydroxymethyl)-5,8a-dimethyl-1,2,3,4,4a,6,7,8-octahydronaphthalen-1-yl]ethyl]-2H-furan-5-one
SMILES CC12CCC(C(C1CCC(C2CCC3=CCOC3=O)CO)(C)CO)O
Standard InChIKey LMOGEODVJJLYGW-UQZPWQSVSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 14-Deoxy-17-hydroxyandrographolide

The herbs of Andrographis paniculata (Burm. f.) Nees

Biological Activity of 14-Deoxy-17-hydroxyandrographolide

TargetsAntifection

14-Deoxy-17-hydroxyandrographolide Dilution Calculator

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14-Deoxy-17-hydroxyandrographolide Molarity Calculator

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Preparing Stock Solutions of 14-Deoxy-17-hydroxyandrographolide

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8371 mL 14.1856 mL 28.3712 mL 56.7424 mL 70.928 mL
5 mM 0.5674 mL 2.8371 mL 5.6742 mL 11.3485 mL 14.1856 mL
10 mM 0.2837 mL 1.4186 mL 2.8371 mL 5.6742 mL 7.0928 mL
50 mM 0.0567 mL 0.2837 mL 0.5674 mL 1.1348 mL 1.4186 mL
100 mM 0.0284 mL 0.1419 mL 0.2837 mL 0.5674 mL 0.7093 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 14-Deoxy-17-hydroxyandrographolide

ent-Labdane diterpenoids from Andrographis paniculata.[Pubmed:16562826]

J Nat Prod. 2006 Mar;69(3):319-22.

Six new ent-labdane diterpenoids, 3-O-beta-D-glucopyranosyl-14,19-dideoxyandrographolide (1), 14-Deoxy-17-hydroxyandrographolide (2), 19-O-[beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoyl]-3,14-dideoxyandrographoli de (3), 3-O-beta-d-glucopyranosylandrographolide (4), 12S-hydroxyandrographolide (5), and andrographatoside (6), together with 17 known analogues, were isolated from the aerial parts of Andrographis paniculata. The structures of 1-6 were determined by spectroscopic data analysis. All compounds isolated were evaluated for their inhibitory activity against several bacterial and fungal strains.

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