19-Hydroxybaccatin IIICAS# 78432-78-7 |
Quality Control & MSDS
3D structure
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| Cas No. | 78432-78-7 | SDF | Download SDF |
| PubChem ID | 11969566 | Appearance | Powder |
| Formula | C31H38O12 | M.Wt | 602.6 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)CO)OC(=O)C | ||
| Standard InChIKey | SYDMVWLQJZBPIU-LSOODRMYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The barks of Taxus chinensis
| Description | 1. 19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol are new antitumor taxanes from Taxus wallichiana. |
19-Hydroxybaccatin III Dilution Calculator
19-Hydroxybaccatin III Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.6595 mL | 8.2974 mL | 16.5948 mL | 33.1895 mL | 41.4869 mL |
| 5 mM | 0.3319 mL | 1.6595 mL | 3.319 mL | 6.6379 mL | 8.2974 mL |
| 10 mM | 0.1659 mL | 0.8297 mL | 1.6595 mL | 3.319 mL | 4.1487 mL |
| 50 mM | 0.0332 mL | 0.1659 mL | 0.3319 mL | 0.6638 mL | 0.8297 mL |
| 100 mM | 0.0166 mL | 0.083 mL | 0.1659 mL | 0.3319 mL | 0.4149 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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19-Hydroxybaccatin III, 10-deacetylcephalomannine, and 10-deacetyltaxol: new antitumor taxanes from Taxus wallichiana.[Pubmed:7264680]
J Nat Prod. 1981 May-Jun;44(3):312-9.
Activity-guided, chromatographic fractionation for a polar extract of Taxus wallichiana Zucc. (originally identified as Cephalotaxus mannii Hook.) resulted in the isolation of three new KB cytotoxic taxane derivatives. Nmr and ms spectral analyses permitted their characterization as 19-Hydroxybaccatin III (3), 10-deacetylcephalomannine (4), and 10-deacetyltaxol (5). The latter two compounds, which are also active against PS leukemia in vivo, were observed to be especially labile, each forming equilibrium mixtures with their cytotoxic C-7 epimers (9, 10).
Taxol and its related taxoids from the needles of Taxus sumatrana.[Pubmed:7728941]
Chem Pharm Bull (Tokyo). 1995 Feb;43(2):365-7.
Through bioassay-guided separation of the chemical constituents of the needles of Taxus sumatrana, taxol (1), cephalomannine (2), and a new taxoid 19-hydroxy-13-oxobaccatin III (8) have been isolated together with 7-epi-10-deacetyltaxol (3), 7-epi-10-deacetylcephalomannine (4), baccatin III (5), 19-Hydroxybaccatin III (6), and 10-deacetyl-13-oxobaccatin III (7). The chemical structure of 8 has been elucidated on the bases of its chemical and physicochemical properties.
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