2,3-Dihydro-6-methylginkgetinCAS# 1013649-09-6 |
2D Structure
Quality Control & MSDS
3D structure
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Number of papers citing our products
Cas No. | 1013649-09-6 | SDF | Download SDF |
PubChem ID | 46911278 | Appearance | Powder |
Formula | C33H26O10 | M.Wt | 582.6 |
Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
Synonyms | 2,3-dihydro-6-methoxyamentoflavone | ||
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | 5,7-dihydroxy-8-[5-[(2S)-5-hydroxy-7-methoxy-6-methyl-4-oxo-2,3-dihydrochromen-2-yl]-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one | ||
SMILES | CC1=C(C=C2C(=C1O)C(=O)CC(O2)C3=CC(=C(C=C3)OC)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC=C(C=C6)O)O)O)OC | ||
Standard InChIKey | ALCMEGWPPBQUES-MHZLTWQESA-N | ||
Standard InChI | InChI=1S/C33H26O10/c1-15-25(41-3)14-28-31(32(15)39)23(38)13-27(42-28)17-6-9-24(40-2)19(10-17)29-20(35)11-21(36)30-22(37)12-26(43-33(29)30)16-4-7-18(34)8-5-16/h4-12,14,27,34-36,39H,13H2,1-3H3/t27-/m0/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
2,3-Dihydro-6-methylginkgetin Dilution Calculator
2,3-Dihydro-6-methylginkgetin Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 1.7164 mL | 8.5822 mL | 17.1644 mL | 34.3289 mL | 42.9111 mL |
5 mM | 0.3433 mL | 1.7164 mL | 3.4329 mL | 6.8658 mL | 8.5822 mL |
10 mM | 0.1716 mL | 0.8582 mL | 1.7164 mL | 3.4329 mL | 4.2911 mL |
50 mM | 0.0343 mL | 0.1716 mL | 0.3433 mL | 0.6866 mL | 0.8582 mL |
100 mM | 0.0172 mL | 0.0858 mL | 0.1716 mL | 0.3433 mL | 0.4291 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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beta-Secretase (BACE-1) inhibitory effect of biflavonoids.[Pubmed:20598535]
Bioorg Med Chem Lett. 2010 Aug 1;20(15):4558-60.
Here, we describe amentoflavone-type biflavonoids, which were isolated from natural sources and were found to inhibit beta-secretase (BACE-1). The structure-activity relationship was studied, and compounds 1-8, 10, 17, and 18 showed BACE-1 inhibitory activity. Among these compounds, 2,3-dihydroamentoflavone 17 and 2,3-Dihydro-6-methylginkgetin 18 exhibited potent inhibitory effects with IC(50) values of 0.75 and 0.35 microM, respectively.