Sonderianol

CAS# 85563-65-1

Sonderianol

Catalog No. BCN9559----Order now to get a substantial discount!

Product Name & Size Price Stock
Sonderianol: 5mg $903 In Stock
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Quality Control of Sonderianol

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Chemical structure

Sonderianol

3D structure

Chemical Properties of Sonderianol

Cas No. 85563-65-1 SDF Download SDF
PubChem ID 15127169 Appearance Powder
Formula C20H26O2 M.Wt 298.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4aR,10aS)-8-ethenyl-6-hydroxy-1,1,4a,7-tetramethyl-4,9,10,10a-tetrahydro-3H-phenanthren-2-one
SMILES CC1=C(C=C2C(=C1C=C)CCC3C2(CCC(=O)C3(C)C)C)O
Standard InChIKey MWEHWEZBGQUQSJ-XLIONFOSSA-N
Standard InChI InChI=1S/C20H26O2/c1-6-13-12(2)16(21)11-15-14(13)7-8-17-19(3,4)18(22)9-10-20(15,17)5/h6,11,17,21H,1,7-10H2,2-5H3/t17-,20+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Sonderianol Dilution Calculator

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Sonderianol Molarity Calculator

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Preparing Stock Solutions of Sonderianol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3512 mL 16.756 mL 33.5121 mL 67.0241 mL 83.7802 mL
5 mM 0.6702 mL 3.3512 mL 6.7024 mL 13.4048 mL 16.756 mL
10 mM 0.3351 mL 1.6756 mL 3.3512 mL 6.7024 mL 8.378 mL
50 mM 0.067 mL 0.3351 mL 0.6702 mL 1.3405 mL 1.6756 mL
100 mM 0.0335 mL 0.1676 mL 0.3351 mL 0.6702 mL 0.8378 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Sonderianol

Two new sesquiterpenoids from endophytic fungus J3 isolated from Mangrove Plant Ceriops tagal.[Pubmed:25060947]

Arch Pharm Res. 2015;38(5):673-6.

Two new sesquiterpenoids, named 2alpha-hydroxyxylaranol B (1) and 4beta-hydroxyxylaranol B (2), together with a known diterpenoid 3,4-seco-Sonderianol (3) were isolated from the fermentation of endophytic fungus J3 of Ceriops tagal. Their structures were elucidated based on spectroscopic methods including 1D and 2D NMR (HMQC, (1)H-(1)H COSY and HMBC). All compounds were evaluated for their cytotoxic activities by MTT method, and compound 3 exhibited cytotoxic activities against K562, SGC-7901, and BEL-7402 cell lines.

Antimicrobial diterpenes from Trigonostemon chinensis.[Pubmed:18611050]

J Nat Prod. 2008 Aug;71(8):1414-7.

Five new diterpenes, trigonochinenes A-E (1-5), and two known ones, 3,4- seco-Sonderianol (6) and 3,4- seco-sonderianic acid (7), were isolated from the aerial part of Trigonostemon chinensis. Compounds 1-4 possess a rare 3,4-seco-cleistanthanic skeleton, and compound 5 is a highly aromatized tetranorditerpene. Structures of these compounds were elucidated by spectroscopic analysis. The antimicrobial activities of compounds 1-7 were evaluated against a panel of bacteria and fungi.

Seco-terpenoids and other constituents from Elateriospermum tapos.[Pubmed:18179177]

J Nat Prod. 2008 Feb;71(2):292-4.

Two new taraxerane triterpenes, 2,3-seco-taraxer-14-ene-2,3,28-trioic acid 2,3-dimethyl ester ( 1) and 2,3-seco-taraxer-14-ene-2,3,28-trioic acid 3-methyl ester ( 2), along with two known triterpenes, hopenol B and aleuritolic acid, and five known flavonoids, putraflavone, kaempferol, sequoiaflavone, amentoflavone, and ginkgetin, were isolated from the leaves of Elateriospermum tapos. The stem extract yielded a new cleistanthane diterpene, 2,3-seco-Sonderianol ( 3), three known triterpenes, lupeol, lupeol acetate, and 3-acetylaleuritolic acid, and three known diterpenes, yucalexin B-22, yucalexin P-15, and yucalexin P-17. The structures of these compounds were established on the basis of their spectroscopic data. Compound 1 was cytotoxic against NCI-H187 and BC cell lines and also showed in vitro antimycobacterial activity against Mycobacterium tuberculosis.

Structures, biogenetic relationships, and cytotoxicity of pimarane-derived diterpenes from Petalostigma pubescens.[Pubmed:16298402]

Phytochemistry. 2006 Aug;67(16):1708-15.

Extraction of Petalostigma pubescens heartwood followed by chromatographic purifications and crystallizations afforded five tricyclic diterpenes: 5,9-syn-rosanes petalostigmones A and B (1 and 2), the erythroxylane petalostigmone C (3), the norditerpene lactone pubescenone (4), and the known ent-cleistanthane diterpene (-)-Sonderianol (5). The structures and relative stereochemistry were elucidated by means of spectroscopic methods, chemical correlations, and, in the cases of 1 and 4, by X-ray crystallographic analyses. The new isolates 1-4 are assumed to belong to the same absolute configurational family (9alphaCH3) of ent-pimarane-derived diterpenes as the known co-occurring (-)-5 (10alphaCH3). Biogenetic schemes originating from a common ent-copalyl diphosphate intermediate are presented to rationalize the structures of these natural products. A novel ring contraction-ring expansion mechanism is suggested to account for the 7-membered B ring of pubescenone. Compounds 1-5 were evaluated for their cytotoxicity; Sonderianol (5) showed the highest activity against mouse leukemia cell lines L1210, P388 and mouse liver cancer cells HEPA1c1c7.

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