Home >> Research Area >>Natural Products>>Flavonoids>> 2,3-dihydrosciadopitysin

2,3-dihydrosciadopitysin

CAS# 34421-19-7

2,3-dihydrosciadopitysin

Catalog No. BCN4034----Order now to get a substantial discount!

Product Name & Size Price Stock
2,3-dihydrosciadopitysin: 5mg $799 In Stock
2,3-dihydrosciadopitysin: 10mg Please Inquire In Stock
2,3-dihydrosciadopitysin: 20mg Please Inquire Please Inquire
2,3-dihydrosciadopitysin: 50mg Please Inquire Please Inquire
2,3-dihydrosciadopitysin: 100mg Please Inquire Please Inquire
2,3-dihydrosciadopitysin: 200mg Please Inquire Please Inquire
2,3-dihydrosciadopitysin: 500mg Please Inquire Please Inquire
2,3-dihydrosciadopitysin: 1000mg Please Inquire Please Inquire

Quality Control of 2,3-dihydrosciadopitysin

Number of papers citing our products

Chemical structure

2,3-dihydrosciadopitysin

3D structure

Chemical Properties of 2,3-dihydrosciadopitysin

Cas No. 34421-19-7 SDF Download SDF
PubChem ID 91886695 Appearance Yellow powder
Formula C33H26O10 M.Wt 582.6
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5,7-dihydroxy-8-[5-[(2S)-5-hydroxy-7-methoxy-4-oxo-2,3-dihydrochromen-2-yl]-2-methoxyphenyl]-2-(4-methoxyphenyl)chromen-4-one
SMILES COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)C4=C(C=CC(=C4)C5CC(=O)C6=C(C=C(C=C6O5)OC)O)OC
Standard InChIKey IHBQEDJQLPQAHW-NDEPHWFRSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 2,3-dihydrosciadopitysin

The hertwoods of Podocarpus macrophyllus

Biological Activity of 2,3-dihydrosciadopitysin

DescriptionStandard reference
In vitro

New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.[Pubmed: 17473463]

Chem Pharm Bull (Tokyo). 2007 May;55(5):757-61.

A new biflavonoid, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), and five known compounds, (-)-catechin (1), quercetin (2), 2,3-dihydrosciadopitysin (3), sciadopitysin (4), and isoginkgetin (6), were isolated from Podocarpus macrophyllus var. macrophyllus (Podocarpaceae). These compounds were evaluated their ability to inhibit cellular tyrosinase activity and for their melanin inhibitory activity in human epidermal melanocytes (HEMn).
METHODS AND RESULTS:
In the melanin synthesis assay, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5) showed a potent anti-tyrosinase effect with IC(50)=0.098 mM in HEMn. It also significantly decreased both protein and mRNA levels of the tyrosinase-related protein-2 (TRP-2) by Western blot and quantitative real-time PCR (qRT-PCR) analysis.
CONCLUSIONS:
These findings suggest that the new compound, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), is the most active component of P. macrophyllus var. macrophyllus in inhibiting pigmentation and that this inhibition is exerted through inhibition of transcription of the genes encoding TRP2.

Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.[Pubmed: 12622229]

Z Naturforsch C. 2003 Jan-Feb;58(1-2):65-9.

Bilobetin and 4'''-O-methylamentoflavone were isolated and identified in the needles of Taxus baccata, for the first time in this species.
METHODS AND RESULTS:
The antifungal activity of biflavones from T. baccata and Ginkgo biloba, namely amentoflavone, 7-O-methylamentoflavone, bilobetin, ginkgetin, sciadopitysin and 2,3-dihydrosciadopitysin towards the fungi Alternaria alternata, Fusarium culmorum, Cladosporium oxysporum was determined employing computer-aided image analysis couplet to a microscope.
CONCLUSIONS:
Bilobetin exhibited a significant antifungal activity with values of ED50 14, 11 and 17 microM respectively. This compound completely inhibited the growth of germinating tubes of Cladosporium oxysporum and Fusarium culmorum at a concentration 100 microM. Activity of ginkgetin and 7-O-methylamentoflavone towards Alternaria alternata was stronger than that of bilobetin. Moreover, slight structural changes in the cell wall of Alternaria alternata exposed to ginkgetin at concentration of 200 microM were observed.

2,3-dihydrosciadopitysin Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

2,3-dihydrosciadopitysin Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 2,3-dihydrosciadopitysin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7164 mL 8.5822 mL 17.1644 mL 34.3289 mL 42.9111 mL
5 mM 0.3433 mL 1.7164 mL 3.4329 mL 6.8658 mL 8.5822 mL
10 mM 0.1716 mL 0.8582 mL 1.7164 mL 3.4329 mL 4.2911 mL
50 mM 0.0343 mL 0.1716 mL 0.3433 mL 0.6866 mL 0.8582 mL
100 mM 0.0172 mL 0.0858 mL 0.1716 mL 0.3433 mL 0.4291 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 2,3-dihydrosciadopitysin

New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.[Pubmed:17473463]

Chem Pharm Bull (Tokyo). 2007 May;55(5):757-61.

A new biflavonoid, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), and five known compounds, (-)-catechin (1), quercetin (2), 2,3-dihydrosciadopitysin (3), sciadopitysin (4), and isoginkgetin (6), were isolated from Podocarpus macrophyllus var. macrophyllus (Podocarpaceae). These compounds were evaluated their ability to inhibit cellular tyrosinase activity and for their melanin inhibitory activity in human epidermal melanocytes (HEMn). In the melanin synthesis assay, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5) showed a potent anti-tyrosinase effect with IC(50)=0.098 mM in HEMn. It also significantly decreased both protein and mRNA levels of the tyrosinase-related protein-2 (TRP-2) by Western blot and quantitative real-time PCR (qRT-PCR) analysis. These findings suggest that the new compound, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), is the most active component of P. macrophyllus var. macrophyllus in inhibiting pigmentation and that this inhibition is exerted through inhibition of transcription of the genes encoding TRP2.

Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba.[Pubmed:12622229]

Z Naturforsch C. 2003 Jan-Feb;58(1-2):65-9.

Bilobetin and 4'''-O-methylamentoflavone were isolated and identified in the needles of Taxus baccata, for the first time in this species. The antifungal activity of biflavones from T. baccata and Ginkgo biloba, namely amentoflavone, 7-O-methylamentoflavone, bilobetin, ginkgetin, sciadopitysin and 2,3-dihydrosciadopitysin towards the fungi Alternaria alternata, Fusarium culmorum, Cladosporium oxysporum was determined employing computer-aided image analysis couplet to a microscope. Bilobetin exhibited a significant antifungal activity with values of ED50 14, 11 and 17 microM respectively. This compound completely inhibited the growth of germinating tubes of Cladosporium oxysporum and Fusarium culmorum at a concentration 100 microM. Activity of ginkgetin and 7-O-methylamentoflavone towards Alternaria alternata was stronger than that of bilobetin. Moreover, slight structural changes in the cell wall of Alternaria alternata exposed to ginkgetin at concentration of 200 microM were observed.

Keywords:

2,3-dihydrosciadopitysin,34421-19-7,Natural Products, buy 2,3-dihydrosciadopitysin , 2,3-dihydrosciadopitysin supplier , purchase 2,3-dihydrosciadopitysin , 2,3-dihydrosciadopitysin cost , 2,3-dihydrosciadopitysin manufacturer , order 2,3-dihydrosciadopitysin , high purity 2,3-dihydrosciadopitysin

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: